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Testosterone Replacement, Low T, HCG, & Beyond
Prostate Related Issues
TRT and prostate cancer
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<blockquote data-quote="madman" data-source="post: 191029" data-attributes="member: 13851"><p><strong>Controversies with testosterone therapy <span style="color: rgb(184, 49, 47)">(2020)</span></strong></p><p><span style="color: rgb(44, 130, 201)">Mohit Khera, MD</span></p><p><span style="color: rgb(44, 130, 201)">Department of Urology, Baylor College of Medicine, Houston, Texas, USA </span></p><p></p><p></p><p><strong>Conclusions</strong></p><p><strong></strong></p><p><strong><em>Clinicians prescribing testosterone should be aware of the current controversies associated with TTh. <span style="color: rgb(184, 49, 47)">Controversies associated with TTh include the potential risk of developing prostate cancer and the worsening of LUTS. In addition, there are concerns about TTh potentially increasing CV risk.</span> </em></strong><em><strong><span style="color: rgb(44, 130, 201)"><u>The current literature does not suggest that there is a significant risk with TTh and prostate cancer, LUTS, and CV events. However, more studies, including randomized placebo-controlled trials, are needed</u>.</span> Clinicians prescribing TTh should also be aware that the majority of hypogonadal patients currently being treated with TTh are being treated off-label. Finally, lifestyle modification, such as weight loss and improvement in sleep, as well as varicocelectomy, can improve serum T values. Patients should be counseled appropriately regarding the indications for T therapy and the benefits of lifestyle modification prior to initiating TTh.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 191029, member: 13851"] [B]Controversies with testosterone therapy [COLOR=rgb(184, 49, 47)](2020)[/COLOR][/B] [COLOR=rgb(44, 130, 201)]Mohit Khera, MD Department of Urology, Baylor College of Medicine, Houston, Texas, USA [/COLOR] [B]Conclusions [I]Clinicians prescribing testosterone should be aware of the current controversies associated with TTh. [COLOR=rgb(184, 49, 47)]Controversies associated with TTh include the potential risk of developing prostate cancer and the worsening of LUTS. In addition, there are concerns about TTh potentially increasing CV risk.[/COLOR] [/I][/B][I][B][COLOR=rgb(44, 130, 201)][U]The current literature does not suggest that there is a significant risk with TTh and prostate cancer, LUTS, and CV events. However, more studies, including randomized placebo-controlled trials, are needed[/U].[/COLOR] Clinicians prescribing TTh should also be aware that the majority of hypogonadal patients currently being treated with TTh are being treated off-label. Finally, lifestyle modification, such as weight loss and improvement in sleep, as well as varicocelectomy, can improve serum T values. Patients should be counseled appropriately regarding the indications for T therapy and the benefits of lifestyle modification prior to initiating TTh.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Prostate Related Issues
TRT and prostate cancer
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