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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
TRT and Gout questions
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<blockquote data-quote="Nelson Vergel" data-source="post: 279171" data-attributes="member: 3"><p>Testosterone therapy has been observed to elevate serum uric acid levels, which may increase the risk of gout[5]. A study of 1899 men found that low testosterone levels were significantly associated with an increased risk of hyperuricemia, a precursor to gout[2]. This suggests that testosterone therapy may be a risk factor for gout, although further research is needed to confirm these findings. It is also important to note that hormonal influences, such as estrogen therapy, can affect plasma uric acid and urinary uric acid levels, which may contribute to the development of acute attacks of gout[1]. Therefore, it is crucial to consider the potential hormonal impacts on uric acid metabolism when evaluating gout risk and treatment options.</p><p></p><p>Citations:</p><p>[1] <a href="https://link.springer.com/chapter/10.1007/978-1-4615-9140-5_11" target="_blank">Hormonal Aspects of Gouty Patients</a></p><p>[2] <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148059/" target="_blank">The Association between Serum Testosterone and Hyperuricemia in Males</a></p><p>[3] <a href="https://www.mdpi.com/2073-4425/11/7/721" target="_blank">The Potential Effect of Aberrant Testosterone Levels on Common Diseases: A Mendelian Randomization Study</a></p><p>[4] <a href="https://tau.amegroups.org/article/view/57817/html" target="_blank">Exploration of the association between serum uric acid and testosterone in adult males: NHANES 2011–2016 - Han - Translational Andrology and Urology</a></p><p>[5] <a href="https://www.jstage.jst.go.jp/article/endocrj/60/12/60_EJ13-0203/_article" target="_blank">Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 279171, member: 3"] Testosterone therapy has been observed to elevate serum uric acid levels, which may increase the risk of gout[5]. A study of 1899 men found that low testosterone levels were significantly associated with an increased risk of hyperuricemia, a precursor to gout[2]. This suggests that testosterone therapy may be a risk factor for gout, although further research is needed to confirm these findings. It is also important to note that hormonal influences, such as estrogen therapy, can affect plasma uric acid and urinary uric acid levels, which may contribute to the development of acute attacks of gout[1]. Therefore, it is crucial to consider the potential hormonal impacts on uric acid metabolism when evaluating gout risk and treatment options. Citations: [1] [URL="https://link.springer.com/chapter/10.1007/978-1-4615-9140-5_11"]Hormonal Aspects of Gouty Patients[/URL] [2] [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148059/"]The Association between Serum Testosterone and Hyperuricemia in Males[/URL] [3] [URL="https://www.mdpi.com/2073-4425/11/7/721"]The Potential Effect of Aberrant Testosterone Levels on Common Diseases: A Mendelian Randomization Study[/URL] [4] [URL="https://tau.amegroups.org/article/view/57817/html"]Exploration of the association between serum uric acid and testosterone in adult males: NHANES 2011–2016 - Han - Translational Andrology and Urology[/URL] [5] [URL="https://www.jstage.jst.go.jp/article/endocrj/60/12/60_EJ13-0203/_article"]Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
TRT and Gout questions
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