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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT and AAS Effect on Adrenals
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<blockquote data-quote="Nelson Vergel" data-source="post: 275043" data-attributes="member: 3"><p>Just found thiis</p><p></p><p>Testosterone can have various effects on cortisol levels. Research has shown that testosterone may decrease cortisol reactivity to stress and suppress cortisol responses to pharmacological stimulation of the hypothalamic-pituitary-adrenal (HPA) axis in men[1][3]. Additionally, there is evidence of an inverse relationship between cortisol and testosterone, where the administration of cortisol can lead to reduced blood testosterone levels[2]. However, some studies have found that testosterone administration has no significant effect on basal cortisol release[1][5]. The relationship between testosterone and cortisol is complex and may be influenced by factors such as the specific context of administration and the individual's characteristics. Therefore, the impact of testosterone on cortisol levels is not fully understood and requires further research to elucidate the underlying mechanisms.</p><p></p><p>For more information, you can refer to the provided sources.</p><p></p><p>Sources</p><p>[1] Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men <a href="https://www.frontiersin.org/articles/10.3389/fphar.2019.01397/full" target="_blank">Frontiers | Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men</a></p><p>[2] Relationship Between Circulating Cortisol and Testosterone: Influence of Physical Exercise <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880087/" target="_blank">Relationship Between Circulating Cortisol and Testosterone: Influence of Physical Exercise</a></p><p>[3] Exogenous testosterone enhances cortisol and affective responses to social-evaluative stress in dominant men <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798202/" target="_blank">Exogenous testosterone enhances cortisol and affective responses to social-evaluative stress in dominant men</a></p><p>[4] Testosterone Suppression of CRH-stimulated Cortisol in Men <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470424/" target="_blank">Testosterone Suppression of CRH-stimulated Cortisol in Men</a></p><p>[5] Effects of Testosterone Administration on Nocturnal Cortisol Secretion in Healthy Older Men <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954240/" target="_blank">Effects of Testosterone Administration on Nocturnal Cortisol Secretion in Healthy Older Men</a></p><p></p><p>By Perplexity at <a href="https://www.perplexity.ai/search/4e78f58b-fd62-4237-93d6-6b3f6f853b76" target="_blank">https://www.perplexity.ai/search/4e78f58b-fd62-4237-93d6-6b3f6f853b76</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 275043, member: 3"] Just found thiis Testosterone can have various effects on cortisol levels. Research has shown that testosterone may decrease cortisol reactivity to stress and suppress cortisol responses to pharmacological stimulation of the hypothalamic-pituitary-adrenal (HPA) axis in men[1][3]. Additionally, there is evidence of an inverse relationship between cortisol and testosterone, where the administration of cortisol can lead to reduced blood testosterone levels[2]. However, some studies have found that testosterone administration has no significant effect on basal cortisol release[1][5]. The relationship between testosterone and cortisol is complex and may be influenced by factors such as the specific context of administration and the individual's characteristics. Therefore, the impact of testosterone on cortisol levels is not fully understood and requires further research to elucidate the underlying mechanisms. For more information, you can refer to the provided sources. Sources [1] Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men [URL="https://www.frontiersin.org/articles/10.3389/fphar.2019.01397/full"]Frontiers | Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men[/URL] [2] Relationship Between Circulating Cortisol and Testosterone: Influence of Physical Exercise [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880087/"]Relationship Between Circulating Cortisol and Testosterone: Influence of Physical Exercise[/URL] [3] Exogenous testosterone enhances cortisol and affective responses to social-evaluative stress in dominant men [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798202/"]Exogenous testosterone enhances cortisol and affective responses to social-evaluative stress in dominant men[/URL] [4] Testosterone Suppression of CRH-stimulated Cortisol in Men [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470424/"]Testosterone Suppression of CRH-stimulated Cortisol in Men[/URL] [5] Effects of Testosterone Administration on Nocturnal Cortisol Secretion in Healthy Older Men [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954240/"]Effects of Testosterone Administration on Nocturnal Cortisol Secretion in Healthy Older Men[/URL] By Perplexity at [URL]https://www.perplexity.ai/search/4e78f58b-fd62-4237-93d6-6b3f6f853b76[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT and AAS Effect on Adrenals
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