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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
TRT & Alzheimer's: A Pilot Study
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<blockquote data-quote="CoastWatcher" data-source="post: 82433" data-attributes="member: 2624"><p>Researchers hypothesized that TRT in older, hypogonadal men would improve cognition. </p><p></p><ul> <li data-xf-list-type="ul">Thirty six patients with a new diagnosis of Alzheimer's Disease were screened for hypogonadism.</li> <li data-xf-list-type="ul">Ten of these patients, 28% had total testosterone values of less than 240 ng/dl and were enrolled in a pilot study - five received testosterone and five received a placebo.</li> <li data-xf-list-type="ul">The protocol administered, 200mg of testosterone cypionate every two weeks, was a poor one (date of study was 2003).</li> <li data-xf-list-type="ul">Measurement of total testosterone, CBC, PSA, and lipids was done at the three, six, nine, and twelve month mark of treatment.</li> <li data-xf-list-type="ul">Total testosterone increased, a mean rise of 126.4 ng/dl, (meaning men were still hyogonadal in terms of symptoms).</li> </ul><p></p><p>In terms of Alzheimer-related symptoms, those in the group receiving testosterone all posted increased scores on Alzheimer's Disease Assessment Scale, and the Mini Mental Status Exam. </p><p></p><p>A small study, with a flawed testosterone protocol figuring prominently, nonetheless suggests that cognition can be positively influenced in Alzheimer's patients with the administration of testosterone.</p><p></p><p><em>Aging Male, 2003 March 6</em></p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/m/pubmed/12809076/?i=4&from=/28914204/related" target="_blank">https://www.ncbi.nlm.nih.gov/m/pubmed/12809076/?i=4&from=/28914204/related</a></p></blockquote><p></p>
[QUOTE="CoastWatcher, post: 82433, member: 2624"] Researchers hypothesized that TRT in older, hypogonadal men would improve cognition. [LIST] [*]Thirty six patients with a new diagnosis of Alzheimer's Disease were screened for hypogonadism. [*]Ten of these patients, 28% had total testosterone values of less than 240 ng/dl and were enrolled in a pilot study - five received testosterone and five received a placebo. [*]The protocol administered, 200mg of testosterone cypionate every two weeks, was a poor one (date of study was 2003). [*]Measurement of total testosterone, CBC, PSA, and lipids was done at the three, six, nine, and twelve month mark of treatment. [*]Total testosterone increased, a mean rise of 126.4 ng/dl, (meaning men were still hyogonadal in terms of symptoms). [/LIST] In terms of Alzheimer-related symptoms, those in the group receiving testosterone all posted increased scores on Alzheimer's Disease Assessment Scale, and the Mini Mental Status Exam. A small study, with a flawed testosterone protocol figuring prominently, nonetheless suggests that cognition can be positively influenced in Alzheimer's patients with the administration of testosterone. [I]Aging Male, 2003 March 6[/I] [URL]https://www.ncbi.nlm.nih.gov/m/pubmed/12809076/?i=4&from=/28914204/related[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
TRT & Alzheimer's: A Pilot Study
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