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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Trough Total Testosterone on once weekly injections
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<blockquote data-quote="madman" data-source="post: 274314" data-attributes="member: 13851"><p>Keep in mind that although TT is important to know FT is what truly matters as it is the active unbound fraction of T responsible for the positive effects.</p><p></p><p>Need to know where your trough FT level truly sits.</p><p></p><p>You are hitting a descent trough (7 days post-injection) TT 540 ng/dL but what is your SHBG and where does your trough FT sit?</p><p></p><p>The kicker here too is your peak TT, FT, and estradiol are going to be much higher.</p><p></p><p>Need to post labs with assays/reference ranges (TT, FT, and estradiol).</p><p></p><p>Throw SHBG in there too.</p><p></p><p>Bumping up your weekly T dose by 50 mg is a huge jump and will jack up your TT, FT, and estradiol further let alone drive up your RBCs, hemoglobin, and hematocrit.</p><p></p><p>A far better move would be splitting up your weekly dose and injecting 50mg T twice weekly (every 3.5 days) which will clip the peak--->trough and result in more stable blood levels throughout the week.</p><p></p><p>You will be able to soften your peak and bring up your trough without even needing to increase your weekly dose.</p><p></p><p>If a dose increase is truly needed then I would go 25-30 mg T/week max.</p><p></p><p>Start low and go slow, much easier going up than having to come down.</p><p></p><p>Regardless need to know where your trough FT level truly sits on your current protocol (100 mg T once weekly).</p><p></p><p>Hope you have had your FT tested alone using the most accurate assays (ED/UF).</p><p></p><p>If not you can easily calculate it using the cFTV with your TT, SHBG, and Albumin.</p></blockquote><p></p>
[QUOTE="madman, post: 274314, member: 13851"] Keep in mind that although TT is important to know FT is what truly matters as it is the active unbound fraction of T responsible for the positive effects. Need to know where your trough FT level truly sits. You are hitting a descent trough (7 days post-injection) TT 540 ng/dL but what is your SHBG and where does your trough FT sit? The kicker here too is your peak TT, FT, and estradiol are going to be much higher. Need to post labs with assays/reference ranges (TT, FT, and estradiol). Throw SHBG in there too. Bumping up your weekly T dose by 50 mg is a huge jump and will jack up your TT, FT, and estradiol further let alone drive up your RBCs, hemoglobin, and hematocrit. A far better move would be splitting up your weekly dose and injecting 50mg T twice weekly (every 3.5 days) which will clip the peak--->trough and result in more stable blood levels throughout the week. You will be able to soften your peak and bring up your trough without even needing to increase your weekly dose. If a dose increase is truly needed then I would go 25-30 mg T/week max. Start low and go slow, much easier going up than having to come down. Regardless need to know where your trough FT level truly sits on your current protocol (100 mg T once weekly). Hope you have had your FT tested alone using the most accurate assays (ED/UF). If not you can easily calculate it using the cFTV with your TT, SHBG, and Albumin. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Trough Total Testosterone on once weekly injections
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