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Most urologists I know don't recommend taking a medication orally for the treatment of Premature Ejaculation as it will affect the patient systemically. Simply look at the side effects listed with most of the medications on that list. No one wants to treat their PE just to be given an even worse problem of decreased libido or erectile dysfunction as is the case when taking SSRIs.


The easiest and least expensive way to treat PE is the use of a condom to add a layer of desensitization or by using "squeeze" or "start/stop" techniques. If that is not helpful then I recommend using a topical anesthetic like the Lidocaine/Prilocaine 2.5/2.5% Cream that can be made by a compounding pharmacy or a FDA approved product that was recently released called Promescent, which is a 10% Lidocaine Spray Gel. Just make sure you wash off any excess cream/gel after it's taken it's affect to prevent the transmission to your partner, or wear a condom afterwards to double the desensitization and prevent its transference.


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