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If I was a doctor, I would not check estradiol at baseline and would only check it afterward if real gynecomastia (not nipple sensitivity) is starting. Most men on proper TRT do not have gynecomastia and water retention should not be assumed to be related to high estradiol. Please read all I have written in the second post since this topic really has tired me out after I have shown enough data in the last 10 years.
