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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Tips on how to blend propionate with enanthate (or cypionate)?
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<blockquote data-quote="Cataceous" data-source="post: 224118" data-attributes="member: 38109"><p>My rough estimate for variation about mean serum levels is half of the fraction of testosterone coming from propionate. This assumes the testosterone from the longer ester varies minimally, while testosterone from propionate gives a +/-50% variation in daily levels. With Empower's 4:1 product the result is: 0.5 * 0.837 / (4 * 0.70 + 0.837) = 11.5%. In contrast, the calculation for the 4:3 blend is 0.5 * 3 * 0.837 / (4 * 0.72 + 3 * 0.837) = 23.3%. Translating to the trough as a fraction of peak, the 4:1 blend is 80%, while the 4:3 blend is 62%.</p><p></p><p>This nominally applies to free testosterone, but works pretty well for total testosterone if SHBG doesn't change much and is not extreme. For example, I recently measured peak TT as 700 ng/dL and trough as 420. This yields a variation of 25% about the mean, not far from the calculated value.</p><p></p><p>The usual disclaimer is that the estimate of 50% variation with pure propionate comes from my numbers. Absorption rates may vary significantly between individuals.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 224118, member: 38109"] My rough estimate for variation about mean serum levels is half of the fraction of testosterone coming from propionate. This assumes the testosterone from the longer ester varies minimally, while testosterone from propionate gives a +/-50% variation in daily levels. With Empower's 4:1 product the result is: 0.5 * 0.837 / (4 * 0.70 + 0.837) = 11.5%. In contrast, the calculation for the 4:3 blend is 0.5 * 3 * 0.837 / (4 * 0.72 + 3 * 0.837) = 23.3%. Translating to the trough as a fraction of peak, the 4:1 blend is 80%, while the 4:3 blend is 62%. This nominally applies to free testosterone, but works pretty well for total testosterone if SHBG doesn't change much and is not extreme. For example, I recently measured peak TT as 700 ng/dL and trough as 420. This yields a variation of 25% about the mean, not far from the calculated value. The usual disclaimer is that the estimate of 50% variation with pure propionate comes from my numbers. Absorption rates may vary significantly between individuals. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Tips on how to blend propionate with enanthate (or cypionate)?
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