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General Peptide Use & Information
Thymosin Alpha 1. Any experience here?
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<blockquote data-quote="BigTex" data-source="post: 266752" data-attributes="member: 43589"><p>Very interesting reports from some of you guys. I remember years back I had purchased a few vials but never sold them. So I just did it all myself. I have no idea whether it was effective or not. I very rarely get sick anyway, and probably didn't do enough or for a long enough period of time. But from reading the research on it I am very impressed. </p><p></p><p>I am wondering why we haven't heard more about this peptide in the past 2-3 years.</p><p></p><h2><p style="margin-left: 20px"><em>CONCLUSION</em></p> </h2> <p style="margin-left: 20px"><em>Thymosin alpha 1 is a thymus peptide with recognized immune modulating capacity and biochemical properties. The synthetic analogue of thymosin alpha 1, thymalfasin, induces IL-2 and B cell growth factor production, differentiation of immature cord blood lymphocytes, raises efficiency of macrophage antigen presentation, and the modulation and partial normalization of function and number of T-lymphocytes. The effects of immune stimulation occur through TLR action in both the myeloid and plasmacytoid dendritic cells with production of cytokines. The immunosuppressive effects of the SARS-CoV-2 viral envelope in inducing cytokine storm may be modulated with thymosin alpha 1 therapy. This would be especially beneficial in preventing catastrophic events such as cytokine storm in more severe cases. Thymosin alpha 1 and its synthetic analogue thymalfasin have well-studied safety profiles and are well-tolerated with only minor side effects. Clinical studies have demonstrated the significant role of thymosin alpha 1 in immune and inflammatory responses, and extensive research has shown its effective use in a myriad of diseases ranging from hepatitis and HIV to immune deficiencies and cancers, as well as its use as a vaccine adjuvant.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>Within the context of COVID-19 infection, it has been shown to reduce mortality in those with severe disease and aid in restoring some immune function through increasing thymic activity. Further study would be highly beneficial in determining if thymosin alpha 1 could serve as a therapeutic agent or in combination with other treatments to mitigate the progression and severity of the disease. For this purpose, we can conclude that further studies are mandated for using thymosin alpha 1 in these patients.</em></p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747025/[/URL]</p><p></p><p>Anyway, it on sale here for a pretty decent price </p><h3>Thymosin Alpha 1 – 10mg</h3><p>$49.99</p><p></p><p></p><p>[URL unfurl="true"]https://nusciencepeptides.com/[/URL]</p><p></p><p>FYI</p><ul> <li data-xf-list-type="ul">Daily Dosage: 500mcg of thymosin-alpha 1, delivered via subcutaneous injection.</li> <li data-xf-list-type="ul">Frequency: Once daily.</li> </ul></blockquote><p></p>
[QUOTE="BigTex, post: 266752, member: 43589"] Very interesting reports from some of you guys. I remember years back I had purchased a few vials but never sold them. So I just did it all myself. I have no idea whether it was effective or not. I very rarely get sick anyway, and probably didn't do enough or for a long enough period of time. But from reading the research on it I am very impressed. I am wondering why we haven't heard more about this peptide in the past 2-3 years. [HEADING=1][INDENT][I]CONCLUSION[/I][/INDENT][/HEADING] [INDENT][I]Thymosin alpha 1 is a thymus peptide with recognized immune modulating capacity and biochemical properties. The synthetic analogue of thymosin alpha 1, thymalfasin, induces IL-2 and B cell growth factor production, differentiation of immature cord blood lymphocytes, raises efficiency of macrophage antigen presentation, and the modulation and partial normalization of function and number of T-lymphocytes. The effects of immune stimulation occur through TLR action in both the myeloid and plasmacytoid dendritic cells with production of cytokines. The immunosuppressive effects of the SARS-CoV-2 viral envelope in inducing cytokine storm may be modulated with thymosin alpha 1 therapy. This would be especially beneficial in preventing catastrophic events such as cytokine storm in more severe cases. Thymosin alpha 1 and its synthetic analogue thymalfasin have well-studied safety profiles and are well-tolerated with only minor side effects. Clinical studies have demonstrated the significant role of thymosin alpha 1 in immune and inflammatory responses, and extensive research has shown its effective use in a myriad of diseases ranging from hepatitis and HIV to immune deficiencies and cancers, as well as its use as a vaccine adjuvant.[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]Within the context of COVID-19 infection, it has been shown to reduce mortality in those with severe disease and aid in restoring some immune function through increasing thymic activity. Further study would be highly beneficial in determining if thymosin alpha 1 could serve as a therapeutic agent or in combination with other treatments to mitigate the progression and severity of the disease. For this purpose, we can conclude that further studies are mandated for using thymosin alpha 1 in these patients.[/I][/INDENT] [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747025/[/URL] Anyway, it on sale here for a pretty decent price [HEADING=2]Thymosin Alpha 1 – 10mg[/HEADING] $49.99 [URL unfurl="true"]https://nusciencepeptides.com/[/URL] FYI [LIST] [*]Daily Dosage: 500mcg of thymosin-alpha 1, delivered via subcutaneous injection. [*]Frequency: Once daily. [/LIST] [/QUOTE]
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General Peptide Use & Information
Thymosin Alpha 1. Any experience here?
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