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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Thinking of trying metformin with TRT
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<blockquote data-quote="dnfuss" data-source="post: 152772" data-attributes="member: 15487"><p>I'm sorry that you disagree, but clinical trials nonetheless are indeed the standard for what constitutes proof of hypothesis in the medical community. Anecdotal evidence, meta-analysis, etc. can be, and often are, used to justify opposing points of view; they are not proof of anything. They can suggest potential hypotheses to be tested by randomized clinical trials (preferably double-blind and placebo-controlled), but that is all. I'm aware that they are often offered up as proof in lay publications. That is unfortunate, but it doesn't change what they are: shoddy science and wishful thinking.</p><p></p><p>There are many who have concerns about metformin. See, e.g., the post immediately following the one Vince links to above (Post #20 under <a href="https://www.excelmale.com/forum/threads/a-new-study-explores-anti-aging-properties-of-metformin.3435/#post-28319" target="_blank">A new study explores anti-aging properties of metformin</a>). I don't think at present those concerns should stop its being prescribed for Type II diabetes. But that's as far as the present state of the science would seem to go, at least for now.</p></blockquote><p></p>
[QUOTE="dnfuss, post: 152772, member: 15487"] I'm sorry that you disagree, but clinical trials nonetheless are indeed the standard for what constitutes proof of hypothesis in the medical community. Anecdotal evidence, meta-analysis, etc. can be, and often are, used to justify opposing points of view; they are not proof of anything. They can suggest potential hypotheses to be tested by randomized clinical trials (preferably double-blind and placebo-controlled), but that is all. I'm aware that they are often offered up as proof in lay publications. That is unfortunate, but it doesn't change what they are: shoddy science and wishful thinking. There are many who have concerns about metformin. See, e.g., the post immediately following the one Vince links to above (Post #20 under [URL="https://www.excelmale.com/forum/threads/a-new-study-explores-anti-aging-properties-of-metformin.3435/#post-28319"]A new study explores anti-aging properties of metformin[/URL]). I don't think at present those concerns should stop its being prescribed for Type II diabetes. But that's as far as the present state of the science would seem to go, at least for now. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Thinking of trying metformin with TRT
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