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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Thinking of stopping my AI. Thoughts.
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<blockquote data-quote="Cataceous" data-source="post: 144460" data-attributes="member: 38109"><p>I used the default value of 4.3 for albumin. Calculated free T isn't that sensitive to albumin changes in the normal range, and I did hedge by saying "about".</p><p></p><p>Weird ranges is another problem with direct free T tests. They end up not being comparable with different labs or with proper absolute numbers. For example, as you're finding, LabCorp's range makes no sense in absolute terms. We know that typically free testosterone is 2-3% of total. At TT of 600 ng/dL this means free T would be around 12-18 ng/dL or 120-180 pg/mL. LabCorp's range is ridiculously low. As bad as this is, it's worse that these tests seem to have large standard deviations and other systematic accuracy problems. Best to not use them. Most guys should always get SHBG with total T and calculate free T. But if you want to see if the "sticky" SHBG idea holds up then you'd need to use one of the fancier free T tests—many times.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 144460, member: 38109"] I used the default value of 4.3 for albumin. Calculated free T isn't that sensitive to albumin changes in the normal range, and I did hedge by saying "about". Weird ranges is another problem with direct free T tests. They end up not being comparable with different labs or with proper absolute numbers. For example, as you're finding, LabCorp's range makes no sense in absolute terms. We know that typically free testosterone is 2-3% of total. At TT of 600 ng/dL this means free T would be around 12-18 ng/dL or 120-180 pg/mL. LabCorp's range is ridiculously low. As bad as this is, it's worse that these tests seem to have large standard deviations and other systematic accuracy problems. Best to not use them. Most guys should always get SHBG with total T and calculate free T. But if you want to see if the "sticky" SHBG idea holds up then you'd need to use one of the fancier free T tests—many times. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Thinking of stopping my AI. Thoughts.
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