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<blockquote data-quote="Gman86" data-source="post: 267116" data-attributes="member: 15043"><p>Another interesting thing about how the body regulates free T is it’s desire to maintain homeostasis. These two sets of labs that I had done are a good example of it. As u can see, my protocol was basically the same during both labs. The only difference is in the first set of labs, I was on arimidex, and the 2nd set of labs I was on the equivalent dose of exemestane. Exemestane is known to lower SHBG, while arimidex does not. So what I assume happened was, in the 2nd set of labs, the exemestane lowered my SHBG, which would have increased my free and bio T levels. But as u can see, my free and bio T levels were basically identical between the two labs. What im assuming my body did while I was on exemestane, was decrease my total T, to maintain the same free and bio T levels as I had before while on arimidex. I could be wrong on the exact mechanisms by which my free and bio T levels remained the same, but the point is the body has very interesting mechanisms to attempt to maintain homeostasis the best that it can. Again, that’s what I’m assuming it was trying to do. </p><p></p><p>Also, as a side note, these labs confirm that E2 is in fact the main stimulator of prolactin production, in the male body. These are some of the lowest prolactin levels I’ve ever had, and it’s simply because I basically bottomed out my E2 levels on the dosages of arimidex and exemestane I was taking at the time </p><p></p><p>and another side note lol. For anyone wondering what the equivalent dose of exemestane and arimidex are, for most guys, it’s basically 1:1. A full 1mg tab of arimidex is basically equivalent to a full 25mg tab of exemestane</p><p></p><p></p><p></p><p>8-15-17 labs were while on this protocol:</p><p></p><p>Test- 90mg split into EOD dosing</p><p></p><p>HCG - 800IU split into EOD dosing (Pregnyl HCG) </p><p></p><p>Arimidex - 0.25mg EOD</p><p></p><p>Total T - 1299 (250-1100 ng/dL) </p><p></p><p>Free T - 146.6 (46.0-224.0) </p><p></p><p>Bio T - 307.8 (110.0-575.0 ng/dL) </p><p></p><p>SHBG 51 (10-50) </p><p></p><p>E2 Sensitive - 8 </p><p></p><p>E2 NOT Sensitive - 13 </p><p></p><p>E2 Free - 0.28 (0.2-1.5) </p><p></p><p>Albumin - 4.6 (3.6-5.1)</p><p></p><p>DHT - 95 (16-79)</p><p></p><p>Prolactin - 3.1 (2.0-18.0)</p><p></p><p></p><p></p><p>12-13-17 labs were while on this protocol:</p><p></p><p>Test- 90mg split into EOD dosing </p><p></p><p>HCG- 800iu split into EOD dosing (Pregnyl HCG)</p><p></p><p>Exemestane - 6.25mg EOD</p><p></p><p>Total T - 974 (250-1100 ng/dL) </p><p></p><p>Free T - 142.6 (46.0-224.0) </p><p></p><p>Bio T - 287.0 (110.0-575.0 ng/dL) </p><p></p><p>SHBG 36 (10-50) </p><p></p><p>E2 Sensitive - 9 </p><p></p><p>E2 NOT Sensitive - 13 </p><p></p><p>E2 Free - 0.28 (0.2-1.5)</p><p></p><p>Albumin - 4.4 (3.6-5.1)</p><p></p><p>DHT - 65 (16-79)</p><p></p><p>Prolactin - 4.5 (2.0-18.0)</p></blockquote><p></p>
[QUOTE="Gman86, post: 267116, member: 15043"] Another interesting thing about how the body regulates free T is it’s desire to maintain homeostasis. These two sets of labs that I had done are a good example of it. As u can see, my protocol was basically the same during both labs. The only difference is in the first set of labs, I was on arimidex, and the 2nd set of labs I was on the equivalent dose of exemestane. Exemestane is known to lower SHBG, while arimidex does not. So what I assume happened was, in the 2nd set of labs, the exemestane lowered my SHBG, which would have increased my free and bio T levels. But as u can see, my free and bio T levels were basically identical between the two labs. What im assuming my body did while I was on exemestane, was decrease my total T, to maintain the same free and bio T levels as I had before while on arimidex. I could be wrong on the exact mechanisms by which my free and bio T levels remained the same, but the point is the body has very interesting mechanisms to attempt to maintain homeostasis the best that it can. Again, that’s what I’m assuming it was trying to do. Also, as a side note, these labs confirm that E2 is in fact the main stimulator of prolactin production, in the male body. These are some of the lowest prolactin levels I’ve ever had, and it’s simply because I basically bottomed out my E2 levels on the dosages of arimidex and exemestane I was taking at the time and another side note lol. For anyone wondering what the equivalent dose of exemestane and arimidex are, for most guys, it’s basically 1:1. A full 1mg tab of arimidex is basically equivalent to a full 25mg tab of exemestane 8-15-17 labs were while on this protocol: Test- 90mg split into EOD dosing HCG - 800IU split into EOD dosing (Pregnyl HCG) Arimidex - 0.25mg EOD Total T - 1299 (250-1100 ng/dL) Free T - 146.6 (46.0-224.0) Bio T - 307.8 (110.0-575.0 ng/dL) SHBG 51 (10-50) E2 Sensitive - 8 E2 NOT Sensitive - 13 E2 Free - 0.28 (0.2-1.5) Albumin - 4.6 (3.6-5.1) DHT - 95 (16-79) Prolactin - 3.1 (2.0-18.0) 12-13-17 labs were while on this protocol: Test- 90mg split into EOD dosing HCG- 800iu split into EOD dosing (Pregnyl HCG) Exemestane - 6.25mg EOD Total T - 974 (250-1100 ng/dL) Free T - 142.6 (46.0-224.0) Bio T - 287.0 (110.0-575.0 ng/dL) SHBG 36 (10-50) E2 Sensitive - 9 E2 NOT Sensitive - 13 E2 Free - 0.28 (0.2-1.5) Albumin - 4.4 (3.6-5.1) DHT - 65 (16-79) Prolactin - 4.5 (2.0-18.0) [/QUOTE]
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