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General Health & Fitness
Nutrition and Supplements
The Importance of the Fatty Acid Transporter L-Carnitine in (NAFLD)
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<blockquote data-quote="madman" data-source="post: 183151" data-attributes="member: 13851"><p>[ATTACH=full]10214[/ATTACH]</p><p><strong><span style="color: rgb(184, 49, 47)">Figure 1.</span> <span style="color: rgb(44, 130, 201)">L-carnitine Synthesis.</span> Endogenous L-carnitine synthesis. L-carnitine is biosynthesized from trimethyl-lysine <span style="color: rgb(184, 49, 47)">(TML)</span>. At least four enzymes are involved in the overall biosynthesis pathway. These are trimethyl-lysine dioxygenase <span style="color: rgb(184, 49, 47)">(TMLD)</span>, 3-hydroxy-N-trimethyllysine aldolase <span style="color: rgb(184, 49, 47)">(HTMLA)</span>, 4-N-trimethylaminobutyraldehyde dehydrogenase <span style="color: rgb(184, 49, 47)">(TMABA-DH)</span> and γ-butyrobetaine dioxygenase <span style="color: rgb(184, 49, 47)">(BBD)</span>. * The double arrow represents additional steps between HTML and γ-butyrobetaine, which are 3-hydroxy-N-trimethyllysine aldolase <span style="color: rgb(184, 49, 47)">(HTMLA)</span> that catalyzes 4-N-trimethylaminobutyraldehyde, which then is catalyzed by 4-N-trimethylaminobutyraldehyde dehydrogenase <span style="color: rgb(184, 49, 47)">(TMABA-DH)</span> into γ-butyrobetaine. </strong></p></blockquote><p></p>
[QUOTE="madman, post: 183151, member: 13851"] [ATTACH type="full"]10214[/ATTACH] [B][COLOR=rgb(184, 49, 47)]Figure 1.[/COLOR] [COLOR=rgb(44, 130, 201)]L-carnitine Synthesis.[/COLOR] Endogenous L-carnitine synthesis. L-carnitine is biosynthesized from trimethyl-lysine [COLOR=rgb(184, 49, 47)](TML)[/COLOR]. At least four enzymes are involved in the overall biosynthesis pathway. These are trimethyl-lysine dioxygenase [COLOR=rgb(184, 49, 47)](TMLD)[/COLOR], 3-hydroxy-N-trimethyllysine aldolase [COLOR=rgb(184, 49, 47)](HTMLA)[/COLOR], 4-N-trimethylaminobutyraldehyde dehydrogenase [COLOR=rgb(184, 49, 47)](TMABA-DH)[/COLOR] and γ-butyrobetaine dioxygenase [COLOR=rgb(184, 49, 47)](BBD)[/COLOR]. * The double arrow represents additional steps between HTML and γ-butyrobetaine, which are 3-hydroxy-N-trimethyllysine aldolase [COLOR=rgb(184, 49, 47)](HTMLA)[/COLOR] that catalyzes 4-N-trimethylaminobutyraldehyde, which then is catalyzed by 4-N-trimethylaminobutyraldehyde dehydrogenase [COLOR=rgb(184, 49, 47)](TMABA-DH)[/COLOR] into γ-butyrobetaine. [/B] [/QUOTE]
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The Importance of the Fatty Acid Transporter L-Carnitine in (NAFLD)
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