ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Nutrition and Supplements
The effect of vitamin D supplementation on the androgenic profile in men: A systematic review and meta‐analysis of clinical trials
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 154793" data-attributes="member: 13851"><p><strong>Abstract </strong></p><p>The aim of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on total testosterone (TT) and sex hormone‐binding globulin (SHBG) in men. We searched PubMed, Scopus and Web of Science for randomized, controlled trials of vitamin D supplementation in men ≥18 years old up to September 2018, without language restrictions. Meta‐analysis was based on a random effects model. The systematic review was registered as CRD42018094498. We identified 3,402 articles, of which eight studies with 10 effect sizes met the inclusion criteria. Vitamin D daily dose equivalents ranged from 600 to 4,000 per day to 60,000 IU per week; duration was 6 weeks to 36 months. In general, vitamin D supplementation had no significant effect on TT (MD = 0.20, 95% CI: −0.20, 0.60, p = 0.336) and SHBG (MD = 1.56, 95% CI: −0.85, 3.97, p = 0.204). Subgroup analysis conducted with duration of prescription, type (daily or weekly), dosing frequency and baseline vitamin D and TT concentration showed that vitamin D did not significantly affect TT. The present study did not find any evidence to support beneficial effect of vitamin D supplementation on TT and SHBG in men. Thus, further large‐scale randomised controlled trials are required to evaluate the effects of vitamin D supplementation on androgen in men.</p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p><strong>5 | CONCLUSION</strong></p><p></p><p><strong>This paper presented outcomes that investigated the effect of vitamin D supplementation on androgen levels in men.</strong> <span style="color: rgb(184, 49, 47)"><strong>The main outcome of this study reaffirmed the null effect of vitamin D supplementation on TT and SHBG in men. </strong></span><span style="color: rgb(44, 130, 201)"><strong>To solve this problem in the future, we recommend further studies that consider the effect of vitamin D over a longer period in men with hypogonadism and severe vitamin D deficiency.</strong></span></p></blockquote><p></p>
[QUOTE="madman, post: 154793, member: 13851"] [B]Abstract [/B] The aim of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on total testosterone (TT) and sex hormone‐binding globulin (SHBG) in men. We searched PubMed, Scopus and Web of Science for randomized, controlled trials of vitamin D supplementation in men ≥18 years old up to September 2018, without language restrictions. Meta‐analysis was based on a random effects model. The systematic review was registered as CRD42018094498. We identified 3,402 articles, of which eight studies with 10 effect sizes met the inclusion criteria. Vitamin D daily dose equivalents ranged from 600 to 4,000 per day to 60,000 IU per week; duration was 6 weeks to 36 months. In general, vitamin D supplementation had no significant effect on TT (MD = 0.20, 95% CI: −0.20, 0.60, p = 0.336) and SHBG (MD = 1.56, 95% CI: −0.85, 3.97, p = 0.204). Subgroup analysis conducted with duration of prescription, type (daily or weekly), dosing frequency and baseline vitamin D and TT concentration showed that vitamin D did not significantly affect TT. The present study did not find any evidence to support beneficial effect of vitamin D supplementation on TT and SHBG in men. Thus, further large‐scale randomised controlled trials are required to evaluate the effects of vitamin D supplementation on androgen in men. [B]5 | CONCLUSION[/B] [B]This paper presented outcomes that investigated the effect of vitamin D supplementation on androgen levels in men.[/B] [COLOR=rgb(184, 49, 47)][B]The main outcome of this study reaffirmed the null effect of vitamin D supplementation on TT and SHBG in men. [/B][/COLOR][COLOR=rgb(44, 130, 201)][B]To solve this problem in the future, we recommend further studies that consider the effect of vitamin D over a longer period in men with hypogonadism and severe vitamin D deficiency.[/B][/COLOR] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Nutrition and Supplements
The effect of vitamin D supplementation on the androgenic profile in men: A systematic review and meta‐analysis of clinical trials
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top