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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
The Development of Gonadotropins for Clinical Use in the Treatment of Infertility
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<blockquote data-quote="madman" data-source="post: 198233" data-attributes="member: 13851"><p><strong>Oral Gonadotropins</strong></p><p><strong></strong></p><p><strong><em>*All gonadotropin preparations have to be injected, which increases the treatment burden for patients. There has therefore been interest in producing a product that can be dosed orally</em></strong>.<strong><em> <u>It is not possible to dose gonadotropins orally because they are proteins and will not be absorbed, rather they are digested by enzymes</u>.</em></strong> As a result of this, attempts to produce an oral drug for ovarian stimulation have focussed on FSH agonists. One oral FSH agonist has been evaluated in healthy females but no effect on follicular development was observed, which was eventually attributed to the low doses used (141). Non-conclusive data is available for this option nowadays.</p></blockquote><p></p>
[QUOTE="madman, post: 198233, member: 13851"] [B]Oral Gonadotropins [I]*All gonadotropin preparations have to be injected, which increases the treatment burden for patients. There has therefore been interest in producing a product that can be dosed orally[/I][/B].[B][I] [U]It is not possible to dose gonadotropins orally because they are proteins and will not be absorbed, rather they are digested by enzymes[/U].[/I][/B] As a result of this, attempts to produce an oral drug for ovarian stimulation have focussed on FSH agonists. One oral FSH agonist has been evaluated in healthy females but no effect on follicular development was observed, which was eventually attributed to the low doses used (141). Non-conclusive data is available for this option nowadays. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
The Development of Gonadotropins for Clinical Use in the Treatment of Infertility
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