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Mental Health
The Case Against Antidepressants
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<blockquote data-quote="electrify" data-source="post: 258002" data-attributes="member: 44439"><p>I'm not for SSRI ADs, but in general, lets say you feel depression symptoms out of nowhere. Even things like Long COVID have caused people to get anhedonia. What are you even supposed to do to solve it? Its really hard for psychological interventions to solve a biological dysfunction so one has to resort to psychiatric intervention, supps/nootropics, hormones, etc. </p><p></p><p>MAOIs seem to be better than SSRIs ironically. Tons of physical side effects but the food interactions are overblown: <a href="https://www.cambridge.org/core/journals/cns-spectrums/article/much-ado-about-nothing-monoamine-oxidase-inhibitors-drug-interactions-and-dietary-tyramine/52112573CADFD3303357C09E80617422" target="_blank">“Much ado about nothing”: monoamine oxidase inhibitors, drug interactions, and dietary tyramine | CNS Spectrums | Cambridge Core</a></p><p></p><p>They also don't have the PSSD risks SSRIs do. </p><p></p><p>Zuranolone the allopregnanolone based AD that hopefully gets approved next month looks promising as well.</p></blockquote><p></p>
[QUOTE="electrify, post: 258002, member: 44439"] I'm not for SSRI ADs, but in general, lets say you feel depression symptoms out of nowhere. Even things like Long COVID have caused people to get anhedonia. What are you even supposed to do to solve it? Its really hard for psychological interventions to solve a biological dysfunction so one has to resort to psychiatric intervention, supps/nootropics, hormones, etc. MAOIs seem to be better than SSRIs ironically. Tons of physical side effects but the food interactions are overblown: [URL="https://www.cambridge.org/core/journals/cns-spectrums/article/much-ado-about-nothing-monoamine-oxidase-inhibitors-drug-interactions-and-dietary-tyramine/52112573CADFD3303357C09E80617422"]“Much ado about nothing”: monoamine oxidase inhibitors, drug interactions, and dietary tyramine | CNS Spectrums | Cambridge Core[/URL] They also don't have the PSSD risks SSRIs do. Zuranolone the allopregnanolone based AD that hopefully gets approved next month looks promising as well. [/QUOTE]
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Mental Health
The Case Against Antidepressants
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