ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Mental Health
The Case Against Antidepressants
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="FunkOdyssey" data-source="post: 234432" data-attributes="member: 44064"><p>I think there are a few possibilities (pure speculation):</p><ol> <li data-xf-list-type="ol">Constantly high testosterone causes some kind of deleterious effects in the brain that are relieved by periods of lower testosterone. This might be mediated by oxidative stress or accumulation of some noxious downstream byproducts.</li> <li data-xf-list-type="ol">Variability in levels might be needed for receptors to remain sensitive in the brain.</li> <li data-xf-list-type="ol">HPTA shutdown is not a binary on/off switch but a continuum. Periods of reduced testosterone and E2 may allow for some tiny blips of HPTA activity that improve well-being, perhaps via neurosteroids. I've seen at least one claim of higher pregnenolone on propionate for example.</li> <li data-xf-list-type="ol">Higher DHT/E2 ratio on propionate may be preferable for some people.</li> </ol><p>I would be interested to know if those who found propionate to be a rollercoaster had tried it SC, because I had that same complaint with IM prop and it is completely gone with SC.</p></blockquote><p></p>
[QUOTE="FunkOdyssey, post: 234432, member: 44064"] I think there are a few possibilities (pure speculation): [LIST=1] [*]Constantly high testosterone causes some kind of deleterious effects in the brain that are relieved by periods of lower testosterone. This might be mediated by oxidative stress or accumulation of some noxious downstream byproducts. [*]Variability in levels might be needed for receptors to remain sensitive in the brain. [*]HPTA shutdown is not a binary on/off switch but a continuum. Periods of reduced testosterone and E2 may allow for some tiny blips of HPTA activity that improve well-being, perhaps via neurosteroids. I've seen at least one claim of higher pregnenolone on propionate for example. [*]Higher DHT/E2 ratio on propionate may be preferable for some people. [/LIST] I would be interested to know if those who found propionate to be a rollercoaster had tried it SC, because I had that same complaint with IM prop and it is completely gone with SC. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Mental Health
The Case Against Antidepressants
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top