ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Mental Health
The Case Against Antidepressants
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="FunkOdyssey" data-source="post: 234204" data-attributes="member: 44064"><p>Tolerance and dependence are building immediately with the clonazepam. If you were to stop now, you would already have rebound anxiety and withdrawal effects, albeit relatively mild. So I think what you're really asking is how long before you cross the threshold where the anti-anxiety effect of your current dose is no longer significant. I do not have any practical experience with that because I never took them consistently enough.</p><p></p><p>If you are trying to use the benzo as a bridge to get onto an antidepressant that would serve as a longer-term anxiety therapy, you would want to start the antidepressant immediately. Otherwise, you are wasting this period of optimal benzo efficacy and building more tolerance and dependence than you need to.</p><p></p><p>It will probably take at least 4-6 weeks for an SSRI to deliver substantial anxiety relief. They often make anxiety worse than baseline when you first start (occasionally much worse), which is partly why this benzo bridge concept is pretty common in the psychiatric treatment of anxiety.</p><p></p><p>Escitalopram (lexapro) is probably the most effective SSRI for anxiety with the least side effects. It is the cleanest SSRI in terms of minimal off-target pharmacological effects and would be my preference here. Sertraline is more stimulating and not as well suited for anxiety. Mirtazapine raises norepinephrine levels tremendously by antagonizing a2 autoreceptors which is not ideal for someone experiencing panic attacks. It will also make you perpetually brain fogged with its strong H1 antagonism.</p><p></p><p>I would start escitalopram at 5 mg daily which strikes a better balance between efficacy and side effects than the typical 10 mg starting dose. You can increase if needed but there are diminishing returns as you move up. I personally could not stand the strongly altered state of consciousness produced by higher doses.</p><p></p><p>Am I understanding correctly that these panic symptoms are only occurring during high intensity gym sessions? Because you are about to take on some serious neurochemical debt with these drugs. You will be borrowing heavily from your future well-being in order to induce states of chemically-induced calmness in the present, and that will debt will have to be repaid in the future with interest. It is hard for me to imagine this as worthwhile only for the ability to work out at maximum capacity. Maybe I don't have the complete picture of how anxiety is affecting you outside of the gym.</p><p></p><p>I am happy to discuss the issues you are having in this thread and it seems like perfectly relevant content.</p></blockquote><p></p>
[QUOTE="FunkOdyssey, post: 234204, member: 44064"] Tolerance and dependence are building immediately with the clonazepam. If you were to stop now, you would already have rebound anxiety and withdrawal effects, albeit relatively mild. So I think what you're really asking is how long before you cross the threshold where the anti-anxiety effect of your current dose is no longer significant. I do not have any practical experience with that because I never took them consistently enough. If you are trying to use the benzo as a bridge to get onto an antidepressant that would serve as a longer-term anxiety therapy, you would want to start the antidepressant immediately. Otherwise, you are wasting this period of optimal benzo efficacy and building more tolerance and dependence than you need to. It will probably take at least 4-6 weeks for an SSRI to deliver substantial anxiety relief. They often make anxiety worse than baseline when you first start (occasionally much worse), which is partly why this benzo bridge concept is pretty common in the psychiatric treatment of anxiety. Escitalopram (lexapro) is probably the most effective SSRI for anxiety with the least side effects. It is the cleanest SSRI in terms of minimal off-target pharmacological effects and would be my preference here. Sertraline is more stimulating and not as well suited for anxiety. Mirtazapine raises norepinephrine levels tremendously by antagonizing a2 autoreceptors which is not ideal for someone experiencing panic attacks. It will also make you perpetually brain fogged with its strong H1 antagonism. I would start escitalopram at 5 mg daily which strikes a better balance between efficacy and side effects than the typical 10 mg starting dose. You can increase if needed but there are diminishing returns as you move up. I personally could not stand the strongly altered state of consciousness produced by higher doses. Am I understanding correctly that these panic symptoms are only occurring during high intensity gym sessions? Because you are about to take on some serious neurochemical debt with these drugs. You will be borrowing heavily from your future well-being in order to induce states of chemically-induced calmness in the present, and that will debt will have to be repaid in the future with interest. It is hard for me to imagine this as worthwhile only for the ability to work out at maximum capacity. Maybe I don't have the complete picture of how anxiety is affecting you outside of the gym. I am happy to discuss the issues you are having in this thread and it seems like perfectly relevant content. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Mental Health
The Case Against Antidepressants
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top