I am on around 53 mg/wk and started close between 80 and 90. Managed that for a year but SHBG lowered and side effects became intolerable (anger, thinking of sex 24/7, no sleep, shakiness, anxiety, brain fog). I have been on a lower dose since around Christmas and feel so much better. Energy is better, sleep very good, word loss has almost disappeared. That is all I take. I am almost 60. Haven't had recent blood levels but not tool long ago I was on 63 mg/wk and levels were quite high. I wish I would have started around 50 mg/wk. I dose EOD.