Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians

Great find madman. I’m right in the age bracket that they are talking about, turning 66 in three months. I agree with the idea that men should be on TRT, but I think they’re selling themselves short:

"The evidence shows that men with age-related low testosterone may experience slight improvements in sexual and erectile function. The evidence does not support prescribing testosterone for men with concerns about energy, vitality, physical function, or cognition."

If they think the testosterone just gives a slight boost to sex drive and slight improvement with erectile dysfunction, they’re missing the boat. I’ve been on for 3 1/2 years and I can tell you that it does improve cognitive ability, energy, muscle growth, and bone density. I’m sure my results are not atypical. dosing protocols are not mentioned and I think that is the key. They also don’t mention the adjustment of lifestyle that is the secret sauce to all this. I’d like to see this research repeated and have the men engage in a more comprehensive program than merely testosterone alone.
 
They also don’t mention the adjustment of lifestyle that is the secret sauce to all this. I’d like to see this research repeated and have the men engage in a more comprehensive program than merely testosterone alone.

I cannot agree more! There's too many men getting wooed by the "low T center" et al commercials that think testosterone is a silver bullet, fountain of youth in a bottle solution. Men are made to be active, both mind and body. I'm a bit behind you in age (turned 42 last month) but I'm in this for life. Every one of us that takes this seriously needs to not only look at our own individual health today, but also at what the guys that are 10+ years ahead of us are doing to stay healthy.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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