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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone Therapy Does Not Increase Risk After Heart Surgery
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<blockquote data-quote="Jinzang" data-source="post: 175055" data-attributes="member: 12925"><p>Examining records of cardiac surgery at the Cleveland Clinic found no increased incidence of cardiac events after the surgery for men on testosterone therapy. <a href="https://journals.lww.com/anesthesia-analgesia/Abstract/2020/04000/Association_of_Testosterone_Replacement_Therapy.16.aspx" target="_blank">The summary</a> says:</p><p></p><p>"Among 20,604 patients who met inclusion and exclusion criteria, 301 patients who used testosterone routinely within 1 month before the surgery were matched to 1505 of 20,303 patients who did not use testosterone. Among the matched cohort, 8 (2.7%) patients in the testosterone group and 45 (3.0%) in the nontestosterone group had ≥1 major cardiovascular adverse event after surgery. The adjusted odds ratio was 0.89 (95% CI, 0.41–1.90; <em>P</em> = .756), comparing testosterone to nontestosterone patients. As for the secondary outcomes, 89 (30%) patients in the testosterone group and 525 (35%) patients in the nontestosterone group had ≥1 minor cardiovascular event. The odds of minor events were not significantly different, with an odds ratio of 0.78 (95% CI, 0.60–1.02; <em>P</em> = .074) comparing testosterone to nontestosterone patients.</p><p></p><p>"Preoperative testosterone is not associated with a statistically significant increased incidence of a composite of postoperative in-hospital mortality and cardiovascular events after cardiac surgery."</p></blockquote><p></p>
[QUOTE="Jinzang, post: 175055, member: 12925"] Examining records of cardiac surgery at the Cleveland Clinic found no increased incidence of cardiac events after the surgery for men on testosterone therapy. [URL='https://journals.lww.com/anesthesia-analgesia/Abstract/2020/04000/Association_of_Testosterone_Replacement_Therapy.16.aspx']The summary[/URL] says: "Among 20,604 patients who met inclusion and exclusion criteria, 301 patients who used testosterone routinely within 1 month before the surgery were matched to 1505 of 20,303 patients who did not use testosterone. Among the matched cohort, 8 (2.7%) patients in the testosterone group and 45 (3.0%) in the nontestosterone group had ≥1 major cardiovascular adverse event after surgery. The adjusted odds ratio was 0.89 (95% CI, 0.41–1.90; [I]P[/I] = .756), comparing testosterone to nontestosterone patients. As for the secondary outcomes, 89 (30%) patients in the testosterone group and 525 (35%) patients in the nontestosterone group had ≥1 minor cardiovascular event. The odds of minor events were not significantly different, with an odds ratio of 0.78 (95% CI, 0.60–1.02; [I]P[/I] = .074) comparing testosterone to nontestosterone patients. "Preoperative testosterone is not associated with a statistically significant increased incidence of a composite of postoperative in-hospital mortality and cardiovascular events after cardiac surgery." [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone Therapy Does Not Increase Risk After Heart Surgery
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