Testosterone, Semen Analysis, and Male Fertility: Expert Advice with Real-Life Journeys on Fertility

madman

Super Moderator
Clomid is old news!

hCG + FSH is where it's at for restoring/maintaining fertility on or off exogenous T!

500IU 3x/week will restore normal ITT.
Protocol is compounded purified preparations of hCG/FSH (3000 IU hCG + 75 IU of FSH) injected subcutaneously 3X/week (M/W/F).

Lipshultz reboot protocol is faster and more effective!

Looking forward the high weekly dose hCG (3000IU 3X weekly) is going to be decreased although some men may need to increase the dose of FSH.




2:38-7:41

How many months do typical guys have to be on this reboot protocol before they might see changes in their sperm concentration?

* we don't start checking until 4 months a full cycle of spermatogenesis, usually we start seeing something by 6 months or between 4 and 8 months and very commonly they are back to normal by 9 months






In the very first episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz sit down with Christian and Heidi, a dynamic vlogging and entrepreneurial couple who are courageously sharing their ongoing infertility journey. Known for building a life together on and off camera, they open up about the challenges they’ve faced in trying to grow their family while balancing their business and personal lives.

Drs. Amy and Larry ask Christian and Heidi about the highs and lows of their path to parenthood, how infertility has affected their relationship, and what they’ve learned along the way. They also discuss what it’s like to bring such a personal journey into the public eye and how they’ve found strength in community and vulnerability.




Key Takeaways:


* Know your numbers. While semen analyses and testosterone levels don’t tell the full story, they are powerful tools to assess fertility and overall health.

* Men considering testosterone therapy should understand that it can completely wipe out sperm production in some cases.





Before starting therapy, it’s essential to:

* Get baseline labs, including semen analysis and hormone panel.

* Explore sperm cryopreservation options.

* Learn about medications like HCG that can support testicular and sperm function while on therapy.




For women, fertility preservation options like egg freezing should be discussed early with a specialist, especially if waiting to have children. And for couples navigating infertility, both partners—not just the woman—should undergo a full evaluation.


This episode is about more than fertility—it’s about awareness, advocacy, and making informed decisions for your future.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

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