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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone, science, and human dignity
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<blockquote data-quote="madman" data-source="post: 223911" data-attributes="member: 13851"><p>[URL unfurl="true"]https://www.auadailynews.org/previews/article/22043674/testosterone-science-and-human-dignity[/URL]</p><p></p><p><strong>The John K. Lattimer Lecture presents new thinking about testosterone treatments for prostate cancer.</strong></p><p><strong></strong></p><p><strong>[ATTACH=full]21806[/ATTACH]</strong></p><p><strong>Abraham Morgentaler, MD, FACS</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong><em>Imagine you had to choose between the quality of your life and the quantity. If there were a treatment that would make your life better but carried a risk of shortening that life, would you take it?</em></strong></p><p></p><p><em>That is a choice many men have been faced with when it comes to testosterone therapy. <strong>For years, the belief that raising testosterone would cause more rapid growth and aggressiveness in prostate cancer prevented many men from seeking it out as a potential therapy.</strong></em></p><p><em></em></p><p><em>But <strong>Abraham Morgentaler</strong>, MD, FACS, associate professor of urology at Beth Israel Deaconess Medical Center at Harvard Medical School in Boston, said<strong> those attitudes are beginning to change and testosterone therapy is improving the quality of life—and dignity—for more men.</strong></em></p><p><em></em></p><p><em>Dr. Morgentaler, who will present this year’s John K. Lattimer Lecture, <strong>“<u>Testosterone, Science and Human Dignity</u>,”</strong> from 10:10 a.m. to 10:30 a.m. on Saturday, May 14, said <strong>the belief that testosterone causes cancer goes back to the 1940s and a study that found lowering testosterone reduced levels of a biomarker called acid phosphatase, which was used in the study. That finding became the basis for managing men with advanced prostate cancer that is still used to this day: androgen deprivation therapy (ADT). <u>Newer research, however, is changing some of those early assumptions about the treatment</u></strong>.</em></p><p><em></em></p><p><em><strong>“The ‘obviousness’ that testosterone is risky for prostate cancer comes from the fact that we still lower testosterone in men with advanced prostate cancer,” </strong>Dr. Morgentaler said. <strong>“So, if lowering testosterone is helpful for prostate cancer, then raising it would logically seem to be dangerous—<u>except that a large set of data has shown this latter statement is not true</u>.”</strong></em></p><p><em><strong></strong></em></p><p><em><strong>Rather than focus on the data, Dr. Morgentaler said he prefers to focus on the human side of the equation. </strong>He cited the case of a 94-year-old researcher with diffuse metastatic disease in his bones and lymph nodes and bilateral nephrostomy tubes from ureteral obstruction.</em></p><p><em></em></p><p><em><strong>“He had been treated with ADT for 6 months, but he hated it because it made him too weak to leave the house,” </strong>he said. <strong>“He sought me out after reading my papers and requested that I treat him with testosterone.</strong> He said, <strong>‘I know I’m going to die eventually—I’m 94 years old! And I’ll probably die from prostate cancer. <u>But while I’m alive, I’d like to live as well as I can</u>.’”</strong></em></p><p><em></em></p><p><em>Dr. Morgentaler said<strong> the man responded well to the testosterone therapy and began exercising and corresponding again with colleagues from around the world. He died 11 months later at 95 years old, </strong>which Dr. Morgentaler said was a reasonable life expectancy for him even without the testosterone treatment.</em></p><p><em></em></p><p><em>Dr. Morgentaler said <strong>he hopes attendees will come away from his lecture with an appreciation for the human element in their profession and a new respect for the tough choices patients will have to make regarding their care.</strong></em></p><p><em><strong></strong></em></p><p><em><strong></strong></em></p><p><em><strong></strong></em></p><p><em><strong>“<u>How we choose to die is really about how we choose to live</u>,” he said. “My hope is that attendees will come to appreciate the lessons I’ve learned over the course of my career, in particular,<u> the need to constantly challenge scientific assumptions and the magnificence of the human spirit</u>.”</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 223911, member: 13851"] [URL unfurl="true"]https://www.auadailynews.org/previews/article/22043674/testosterone-science-and-human-dignity[/URL] [B]The John K. Lattimer Lecture presents new thinking about testosterone treatments for prostate cancer. [ATTACH type="full" alt="Screenshot (13091).png"]21806[/ATTACH] Abraham Morgentaler, MD, FACS [I]Imagine you had to choose between the quality of your life and the quantity. If there were a treatment that would make your life better but carried a risk of shortening that life, would you take it?[/I][/B] [I]That is a choice many men have been faced with when it comes to testosterone therapy. [B]For years, the belief that raising testosterone would cause more rapid growth and aggressiveness in prostate cancer prevented many men from seeking it out as a potential therapy.[/B] But [B]Abraham Morgentaler[/B], MD, FACS, associate professor of urology at Beth Israel Deaconess Medical Center at Harvard Medical School in Boston, said[B] those attitudes are beginning to change and testosterone therapy is improving the quality of life—and dignity—for more men.[/B] Dr. Morgentaler, who will present this year’s John K. Lattimer Lecture, [B]“[U]Testosterone, Science and Human Dignity[/U],”[/B] from 10:10 a.m. to 10:30 a.m. on Saturday, May 14, said [B]the belief that testosterone causes cancer goes back to the 1940s and a study that found lowering testosterone reduced levels of a biomarker called acid phosphatase, which was used in the study. That finding became the basis for managing men with advanced prostate cancer that is still used to this day: androgen deprivation therapy (ADT). [U]Newer research, however, is changing some of those early assumptions about the treatment[/U][/B]. [B]“The ‘obviousness’ that testosterone is risky for prostate cancer comes from the fact that we still lower testosterone in men with advanced prostate cancer,” [/B]Dr. Morgentaler said. [B]“So, if lowering testosterone is helpful for prostate cancer, then raising it would logically seem to be dangerous—[U]except that a large set of data has shown this latter statement is not true[/U].” Rather than focus on the data, Dr. Morgentaler said he prefers to focus on the human side of the equation. [/B]He cited the case of a 94-year-old researcher with diffuse metastatic disease in his bones and lymph nodes and bilateral nephrostomy tubes from ureteral obstruction. [B]“He had been treated with ADT for 6 months, but he hated it because it made him too weak to leave the house,” [/B]he said. [B]“He sought me out after reading my papers and requested that I treat him with testosterone.[/B] He said, [B]‘I know I’m going to die eventually—I’m 94 years old! And I’ll probably die from prostate cancer. [U]But while I’m alive, I’d like to live as well as I can[/U].’”[/B] Dr. Morgentaler said[B] the man responded well to the testosterone therapy and began exercising and corresponding again with colleagues from around the world. He died 11 months later at 95 years old, [/B]which Dr. Morgentaler said was a reasonable life expectancy for him even without the testosterone treatment. Dr. Morgentaler said [B]he hopes attendees will come away from his lecture with an appreciation for the human element in their profession and a new respect for the tough choices patients will have to make regarding their care. “[U]How we choose to die is really about how we choose to live[/U],” he said. “My hope is that attendees will come to appreciate the lessons I’ve learned over the course of my career, in particular,[U] the need to constantly challenge scientific assumptions and the magnificence of the human spirit[/U].”[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone, science, and human dignity
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