ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Articles
Testosterone replacement therapy and its effect on bone marrow
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Nelson Vergel" data-source="post: 273043" data-attributes="member: 3"><p>[h3]</p><p> Table of Contents [/h3]</p><p> [h1]<strong>Abstract</strong>[/h1]</p><p>[h2]<strong> Introduction</strong>[/h2]</p><p>TRT in men with testosterone deficiency syndrome (TDS) had multiple positive effects and restore a quality of life of affected men. Polyglobulia is the most common <strong><a href="https://www.excelmale.com/how-to-increase-testosterone-naturally-2/" target="_blank">dose-limiting</a></strong> adverse effect of TRT, but the mechanisms of TRT-mediated erythropoesis remain unclear. In this study, we evaluated long term haematological side effects of TRT: polyglobulia, elevated hemoglobin (Hb) and haematocrit (Ht).</p><p>[h2]<strong>Methods</strong>[/h2]</p><p>In a cross-sectional descriptive study, the authors treated 69 men with TDS and the average age 59 years and the follow-up period 81.32 months. The men were treated with three-month i.m. injections of 1000 mg testosterone undecanoate. The elevated values were: Hb above 176 g/l, Ht above 0.52 and erythrocytes (Ery) above 6.0 mil/mcl.</p><p>[h2]<strong>Results</strong>[/h2]</p><p>21 out of 69 patients (30.43 %) had an increased Hb, Ht or Ery during treatment. The interesting fact was that only five men (7.24 %) had increased the number of Ery (true polyglobulia). No men with elevated level of Hb, Ht or Ery had other side effects (like thrombosis).</p><p>[h1]<strong>Conclusion</strong>[/h1]</p><p>It is still not clear, why in some men on TRT the feedback does not work and bone marrow production of red blood cells continues even if the upper limit is reached. Authors expect that only 7% of men had true polyglobulia, other men had elevated Hb or Ht. Based on our own experience we recommend a <strong><a href="https://www.discountedlabs.com/blog/free-testosterone-6-ways-to-boost-it" target="_blank">regular check</a></strong> of men on TRT on order to avoid possible serious side-effects</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 273043, member: 3"] [h3] Table of Contents [/h3] [h1][b]Abstract[/b][/h1] [h2][b] Introduction[/b][/h2] TRT in men with testosterone deficiency syndrome (TDS) had multiple positive effects and restore a quality of life of affected men. Polyglobulia is the most common [b][url=https://www.excelmale.com/how-to-increase-testosterone-naturally-2/]dose-limiting[/url][/b] adverse effect of TRT, but the mechanisms of TRT-mediated erythropoesis remain unclear. In this study, we evaluated long term haematological side effects of TRT: polyglobulia, elevated hemoglobin (Hb) and haematocrit (Ht). [h2][b]Methods[/b][/h2] In a cross-sectional descriptive study, the authors treated 69 men with TDS and the average age 59 years and the follow-up period 81.32 months. The men were treated with three-month i.m. injections of 1000 mg testosterone undecanoate. The elevated values were: Hb above 176 g/l, Ht above 0.52 and erythrocytes (Ery) above 6.0 mil/mcl. [h2][b]Results[/b][/h2] 21 out of 69 patients (30.43 %) had an increased Hb, Ht or Ery during treatment. The interesting fact was that only five men (7.24 %) had increased the number of Ery (true polyglobulia). No men with elevated level of Hb, Ht or Ery had other side effects (like thrombosis). [h1][b]Conclusion[/b][/h1] It is still not clear, why in some men on TRT the feedback does not work and bone marrow production of red blood cells continues even if the upper limit is reached. Authors expect that only 7% of men had true polyglobulia, other men had elevated Hb or Ht. Based on our own experience we recommend a [b][url=https://www.discountedlabs.com/blog/free-testosterone-6-ways-to-boost-it]regular check[/url][/b] of men on TRT on order to avoid possible serious side-effects [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Articles
Testosterone replacement therapy and its effect on bone marrow
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top