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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Testosterone preservative toxicity?
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<blockquote data-quote="Dwhit" data-source="post: 76181" data-attributes="member: 15978"><p>I've been having some strange side effects for the past few months: waking up short of breath, brain fog, head pressure, even a couple episodes of nystagmus. I trace these symptoms back to the same time I happened to switch from cypionate to enanthate. I assumed these were essentially interchangeable, and I still think they are, but I happened to look at the package insert for enanthate and discovered that it contains a different preservative: chlorobutanol (the cypionate I used contained the more common benzyl alcohol as a preservative). Well, I looked up chlorobutanol, and lo and behold the side effects include cns depression and nystagmus. Typically this occurs at higher doses than what is contained in a typical T dose, but the half life is 10+ days, so I imagine it builds up in your system over time (benzyl alcohol has a half life of a couple hours). I found one pharmacology textbook that said, chlorobutanol "can cause cns toxicity with chronic use." Hmm... Well, I am posting this message from the pharmacy as I await my new prescription of cypionate. It will probably be a few weeks before I will know if there is a difference. (I also have sleep study pending, and full labs.) I'm curious if any one else has had similar symptoms and if their T contains chlorobutanol.</p></blockquote><p></p>
[QUOTE="Dwhit, post: 76181, member: 15978"] I've been having some strange side effects for the past few months: waking up short of breath, brain fog, head pressure, even a couple episodes of nystagmus. I trace these symptoms back to the same time I happened to switch from cypionate to enanthate. I assumed these were essentially interchangeable, and I still think they are, but I happened to look at the package insert for enanthate and discovered that it contains a different preservative: chlorobutanol (the cypionate I used contained the more common benzyl alcohol as a preservative). Well, I looked up chlorobutanol, and lo and behold the side effects include cns depression and nystagmus. Typically this occurs at higher doses than what is contained in a typical T dose, but the half life is 10+ days, so I imagine it builds up in your system over time (benzyl alcohol has a half life of a couple hours). I found one pharmacology textbook that said, chlorobutanol "can cause cns toxicity with chronic use." Hmm... Well, I am posting this message from the pharmacy as I await my new prescription of cypionate. It will probably be a few weeks before I will know if there is a difference. (I also have sleep study pending, and full labs.) I'm curious if any one else has had similar symptoms and if their T contains chlorobutanol. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Testosterone preservative toxicity?
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