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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone Level: How Low is Too Low? Health Consequences of Low Testosterone
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<blockquote data-quote="Nelson Vergel" data-source="post: 56476" data-attributes="member: 3"><p>The Journal of Clinical Endocrinology & Metabolism 2008 Jan;93(1):68-75.</p><p></p><p><span style="font-size: 12px"><span style="font-family: 'Arial'"><strong>Low Serum Testosterone and Mortality in Older Men. </strong></span></span></p><p></p><p>Gail A. Laughlin, Eliza beth Barrett-Connor and Jaclyn Bergstrom. Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093</p><p></p><p>Results: During an average 11.8-yr follow-up, 538 deaths occurred. Men whose total testosterone levels were in the lowest quartile (<241 ng/dl) were 40% more likely to die than those with higher levels, independent of age, adiposity, and lifestyle. Additional adjustment for health status markers, lipids, lipoproteins, blood pressure, glycemia, adipocytokines, and estradiol levels had minimal effect on results. The low testosterone-mortality association was also independent of the metabolic syndrome, diabetes, and prevalent cardiovascular disease but was attenuated by adjustment for IL-6 and C-reactive protein. In cause-specific analyses, low testosterone predicted an increased risk of cardiovascular and respiratory disease (HR mortality but was not significantly related to cancer death. Results were similar for bioavailable testosterone.</p><p></p><p>Conclusions: Testosterone insufficiency in older men is associated with increased risk of death over the following 20 yr, independent of multiple risk factors and several preexisting health conditions.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 56476, member: 3"] The Journal of Clinical Endocrinology & Metabolism 2008 Jan;93(1):68-75. [SIZE=12px][FONT=Arial][B]Low Serum Testosterone and Mortality in Older Men. [/B][/FONT][/SIZE] Gail A. Laughlin, Eliza beth Barrett-Connor and Jaclyn Bergstrom. Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093 Results: During an average 11.8-yr follow-up, 538 deaths occurred. Men whose total testosterone levels were in the lowest quartile (<241 ng/dl) were 40% more likely to die than those with higher levels, independent of age, adiposity, and lifestyle. Additional adjustment for health status markers, lipids, lipoproteins, blood pressure, glycemia, adipocytokines, and estradiol levels had minimal effect on results. The low testosterone-mortality association was also independent of the metabolic syndrome, diabetes, and prevalent cardiovascular disease but was attenuated by adjustment for IL-6 and C-reactive protein. In cause-specific analyses, low testosterone predicted an increased risk of cardiovascular and respiratory disease (HR mortality but was not significantly related to cancer death. Results were similar for bioavailable testosterone. Conclusions: Testosterone insufficiency in older men is associated with increased risk of death over the following 20 yr, independent of multiple risk factors and several preexisting health conditions. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone Level: How Low is Too Low? Health Consequences of Low Testosterone
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