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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone Level: How Low is Too Low? Health Consequences of Low Testosterone
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<blockquote data-quote="Nelson Vergel" data-source="post: 267307" data-attributes="member: 3"><p><h3>Low Blood Levels of Testosterone and Associated Risks:</h3><h4>< 450 ng/dl (15.3 nmol/l) - Risk of metabolic syndrome</h4> <ul> <li data-xf-list-type="ul">Reference: Dhindsa, S., Miller, M. G., McWhirter, C. L., Mager, D. E., Ghanim, H., Chaudhuri, A., & Dandona, P. (2010). Testosterone concentrations in diabetic and nondiabetic obese men. Diabetes Care, 33(6), 1186-1192. <a href="https://pubmed.ncbi.nlm.nih.gov/20200299/" target="_blank">PubMed</a></li> </ul><h4>< 400 ng/dl (15.3 nmol/l) - Venous leakage (internal penile damage) risk</h4> <ul> <li data-xf-list-type="ul">Reference: Yassin, A. A., & Saad, F. (2017). Testosterone Deficiency and Testosterone Treatment in Older Men. Gerontology, 63(2), 144–156. <a href="https://pubmed.ncbi.nlm.nih.gov/27855453/" target="_blank">PubMed</a></li> </ul><h4>< 350 ng/dl (11.9 nmol/l) – All-cause death risk and anemia risk</h4> <ul> <li data-xf-list-type="ul">Reference: Khaw, K. T., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., ... & Day, N. (2007). Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men. Circulation, 116(23), 2694-2701. <a href="https://pubmed.ncbi.nlm.nih.gov/18040025/" target="_blank">PubMed</a></li> </ul><h4>< 300 ng/dL (10.2 nmol/L) - Lowered libido, weight gain & Diabetes risk increased</h4> <ul> <li data-xf-list-type="ul">Reference: Traish, A. M., Saad, F., & Guay, A. (2009). The dark side of testosterone deficiency: I. Metabolic syndrome and erectile dysfunction. Journal of Andrology, 30(1), 10-22. <a href="https://pubmed.ncbi.nlm.nih.gov/18772488/" target="_blank">PubMed</a></li> </ul><h4>< 300 ng/dL (10.2 nmol/L) - Quartile risk of fractures (osteoporosis), memory-related issues & depression risk increases</h4> <ul> <li data-xf-list-type="ul">Reference: Orwoll, E., Lambert, L. C., Marshall, L. M., Phipps, K., Blank, J., Barrett-Connor, E., ... & Cummings, S. (2006). Testosterone and estradiol among older men. The Journal of Clinical Endocrinology & Metabolism, 91(4), 1336-1344. <a href="https://pubmed.ncbi.nlm.nih.gov/16492693/" target="_blank">PubMed</a></li> </ul><h4>< 250 ng/dl (8.5 nmol/l) - Arterial plaque (arteriosclerosis) & sleep quality affected</h4> <ul> <li data-xf-list-type="ul">Reference: Vlachopoulos, C., Ioakeimidis, N., Miner, M., & Aggelis, A. (2014). Testosterone deficiency: a determinant of aortic stiffness in men. Atherosclerosis, 233(1), 278-283. <a href="https://pubmed.ncbi.nlm.nih.gov/24529131/" target="_blank">PubMed</a></li> </ul><h4>< 235 ng/dl (8.0 nmol/l) - Hardening of arteries (dialysis patients)</h4> <ul> <li data-xf-list-type="ul">Reference: Carrero, J. J., Qureshi, A. R., Parini, P., Arver, S., Lindholm, B., Bárány, P., ... & Stenvinkel, P. (2009). Low serum testosterone increases mortality risk among male dialysis patients. Journal of the American Society of Nephrology, 20(3), 613-620. <a href="https://pubmed.ncbi.nlm.nih.gov/19158322/" target="_blank">PubMed</a></li> </ul><h4>< 200 ng/dl (6.8 nmol/l) - Morning erections decrease</h4> <ul> <li data-xf-list-type="ul">Reference: O'Connor, D. B., Lee, D. M., Corona, G., Forti, G., Tajar, A., O'Neill, T. W., ... & EMAS Study Group. (2011). The relationships between sex hormones and sexual function in middle-aged and older European men. The Journal of Clinical Endocrinology & Metabolism, 96(10), E1577-E1587. <a href="https://pubmed.ncbi.nlm.nih.gov/21816776/" target="_blank">PubMed</a></li> </ul><h4>< 150 ng/dl (5.1 nmol/l) - Increased inflammation (TNF-alpha)</h4> <ul> <li data-xf-list-type="ul">Reference: Malkin, C. J., Pugh, P. J., Jones, R. D., Kapoor, D., Channer, K. S., & Jones, T. H. (2004). The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. The Journal of Clinical Endocrinology & Metabolism, 89(7), 3313-3318. <a href="https://pubmed.ncbi.nlm.nih.gov/15240610/" target="_blank">PubMed</a></li> </ul></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 267307, member: 3"] [HEADING=2]Low Blood Levels of Testosterone and Associated Risks:[/HEADING] [HEADING=3]< 450 ng/dl (15.3 nmol/l) - Risk of metabolic syndrome[/HEADING] [LIST] [*]Reference: Dhindsa, S., Miller, M. G., McWhirter, C. L., Mager, D. E., Ghanim, H., Chaudhuri, A., & Dandona, P. (2010). Testosterone concentrations in diabetic and nondiabetic obese men. Diabetes Care, 33(6), 1186-1192. [URL='https://pubmed.ncbi.nlm.nih.gov/20200299/']PubMed[/URL] [/LIST] [HEADING=3]< 400 ng/dl (15.3 nmol/l) - Venous leakage (internal penile damage) risk[/HEADING] [LIST] [*]Reference: Yassin, A. A., & Saad, F. (2017). Testosterone Deficiency and Testosterone Treatment in Older Men. Gerontology, 63(2), 144–156. [URL='https://pubmed.ncbi.nlm.nih.gov/27855453/']PubMed[/URL] [/LIST] [HEADING=3]< 350 ng/dl (11.9 nmol/l) – All-cause death risk and anemia risk[/HEADING] [LIST] [*]Reference: Khaw, K. T., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., ... & Day, N. (2007). Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men. Circulation, 116(23), 2694-2701. [URL='https://pubmed.ncbi.nlm.nih.gov/18040025/']PubMed[/URL] [/LIST] [HEADING=3]< 300 ng/dL (10.2 nmol/L) - Lowered libido, weight gain & Diabetes risk increased[/HEADING] [LIST] [*]Reference: Traish, A. M., Saad, F., & Guay, A. (2009). The dark side of testosterone deficiency: I. Metabolic syndrome and erectile dysfunction. Journal of Andrology, 30(1), 10-22. [URL='https://pubmed.ncbi.nlm.nih.gov/18772488/']PubMed[/URL] [/LIST] [HEADING=3]< 300 ng/dL (10.2 nmol/L) - Quartile risk of fractures (osteoporosis), memory-related issues & depression risk increases[/HEADING] [LIST] [*]Reference: Orwoll, E., Lambert, L. C., Marshall, L. M., Phipps, K., Blank, J., Barrett-Connor, E., ... & Cummings, S. (2006). Testosterone and estradiol among older men. The Journal of Clinical Endocrinology & Metabolism, 91(4), 1336-1344. [URL='https://pubmed.ncbi.nlm.nih.gov/16492693/']PubMed[/URL] [/LIST] [HEADING=3]< 250 ng/dl (8.5 nmol/l) - Arterial plaque (arteriosclerosis) & sleep quality affected[/HEADING] [LIST] [*]Reference: Vlachopoulos, C., Ioakeimidis, N., Miner, M., & Aggelis, A. (2014). Testosterone deficiency: a determinant of aortic stiffness in men. Atherosclerosis, 233(1), 278-283. [URL='https://pubmed.ncbi.nlm.nih.gov/24529131/']PubMed[/URL] [/LIST] [HEADING=3]< 235 ng/dl (8.0 nmol/l) - Hardening of arteries (dialysis patients)[/HEADING] [LIST] [*]Reference: Carrero, J. J., Qureshi, A. R., Parini, P., Arver, S., Lindholm, B., Bárány, P., ... & Stenvinkel, P. (2009). Low serum testosterone increases mortality risk among male dialysis patients. Journal of the American Society of Nephrology, 20(3), 613-620. [URL='https://pubmed.ncbi.nlm.nih.gov/19158322/']PubMed[/URL] [/LIST] [HEADING=3]< 200 ng/dl (6.8 nmol/l) - Morning erections decrease[/HEADING] [LIST] [*]Reference: O'Connor, D. B., Lee, D. M., Corona, G., Forti, G., Tajar, A., O'Neill, T. W., ... & EMAS Study Group. (2011). The relationships between sex hormones and sexual function in middle-aged and older European men. The Journal of Clinical Endocrinology & Metabolism, 96(10), E1577-E1587. [URL='https://pubmed.ncbi.nlm.nih.gov/21816776/']PubMed[/URL] [/LIST] [HEADING=3]< 150 ng/dl (5.1 nmol/l) - Increased inflammation (TNF-alpha)[/HEADING] [LIST] [*]Reference: Malkin, C. J., Pugh, P. J., Jones, R. D., Kapoor, D., Channer, K. S., & Jones, T. H. (2004). The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. The Journal of Clinical Endocrinology & Metabolism, 89(7), 3313-3318. [URL='https://pubmed.ncbi.nlm.nih.gov/15240610/']PubMed[/URL] [/LIST] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone Level: How Low is Too Low? Health Consequences of Low Testosterone
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