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Where does your HCT sit when it’s “high”. The answer is most likely let your HCT go to where it wants, without donating blood, unless it’s 55+. Even at that level, or slightly above, it’s still debatable whether it’s an issue or not. Platelets being high seems to be the problem when it comes to blood thickening too much, and increasing cardiovascular risk, not high HGB, HCT, or red blood cells. My HCT was recently 53.8, but my platelets were on the low end of normal. I ended up donating, due to Defy wanting me to, but I wasn’t worried about the high HCT. My BP wasn’t elevated above baseline or anything.


With your low SHBG, my advice would be to inject ED, or EOD, and find a dose that keeps your total, and more importantly free testosterone where you want it, and not donate blood unless your HCT gets to around 54-55+.


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