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I don't think it does. Many things contribute to plaque growth. All plaque that grows in the arteries starts as soft plaque. Then it's slowly becomes calcified plaque which is safe stable plaque. Uncontrol plaque growth can grow at 30% a year and that's where the issues come in. The unstable plaque can rupture and cause a blockage which can cause  a heart attack or stroke.


Through exercise your arteries can open up and increase in size. Which will look normal with a  catheterization. Through exercise you can also make shearing which is your body making natural bypasses.


A few years ago my dad had a stent put in his artery going to his kidney because it was blocked and when they looked at it they saw his body was already making a natural bypass.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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