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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone (DHT) and Prostate Enlargement
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<blockquote data-quote="madman" data-source="post: 124323" data-attributes="member: 13851"><p><strong>Collectively, these data indicate that the prostate self-regulates DHT concentrations independently of serum DHT concentrations. Within a broad range from low to high-normal serum testosterone concentrations, prostatic DHT concentrations remain stable. It is likely that even high dosages of testosterone would not affect prostatic DHT concentrations through passive diffusion; serum DHT concentrations would have to exceed normal prostatic DHT concentrations that are typically 10-fold higher than circulating DHT concentrations. <span style="color: rgb(184, 49, 47)">However, very high dosages of testosterone could elevate prostatic DHT concentrations by providing more substrate (testosterone) for prostatic synthesis of DHT</span>. For the prostate, DHT is a paracrine and intracrine hormone, not a classic circulating hormone</strong></p></blockquote><p></p>
[QUOTE="madman, post: 124323, member: 13851"] [B]Collectively, these data indicate that the prostate self-regulates DHT concentrations independently of serum DHT concentrations. Within a broad range from low to high-normal serum testosterone concentrations, prostatic DHT concentrations remain stable. It is likely that even high dosages of testosterone would not affect prostatic DHT concentrations through passive diffusion; serum DHT concentrations would have to exceed normal prostatic DHT concentrations that are typically 10-fold higher than circulating DHT concentrations. [COLOR=rgb(184, 49, 47)]However, very high dosages of testosterone could elevate prostatic DHT concentrations by providing more substrate (testosterone) for prostatic synthesis of DHT[/COLOR]. For the prostate, DHT is a paracrine and intracrine hormone, not a classic circulating hormone[/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone (DHT) and Prostate Enlargement
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