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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone Decreases Leptin Levels in Dieting Men
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<blockquote data-quote="Jinzang" data-source="post: 65507" data-attributes="member: 12925"><p>A secondary analysis of a previous study reported the result.</p><p></p><p>Men in the cohort were randomly assigned either 56 weeks of 1,000 mg intramuscular testosterone undecanoate therapy (Reandron, Bayer; n = 49; cases) or a matching placebo (n = 51; controls); 82 men completed the study. The study was conducted between April 2013 and November 2015. For the secondary analysis, primary outcomes were between-group differences during follow-up in levels of leptin, adiponectin, ghrelin, glucagon-like peptide-1, gastric inhibitory polypeptide, peptide PYY, pancreatic polypeptide and amylin.</p><p></p><p>At 56 weeks, men assigned testosterone therapy had reduced leptin levels vs. controls. Researchers noted that the between-group changes in leptin were dependent on baseline fat mass. There were no significant between-group differences for other hormones at 56 weeks, according to the researchers.</p><p></p><p>The <a href="http://www.healio.com/endocrinology/hormone-therapy/news/in-the-journals/%7B7e304405-3252-40f7-b8ff-777548a84af1%7D/testosterone-therapy-decreases-leptin-levels-in-men-with-obesity" target="_blank">original news report</a>.</p><p></p><p>I have to comment that 1000 mg of testosterone a week is a huge dose, how did they ever get approval for a study like that?</p></blockquote><p></p>
[QUOTE="Jinzang, post: 65507, member: 12925"] A secondary analysis of a previous study reported the result. Men in the cohort were randomly assigned either 56 weeks of 1,000 mg intramuscular testosterone undecanoate therapy (Reandron, Bayer; n = 49; cases) or a matching placebo (n = 51; controls); 82 men completed the study. The study was conducted between April 2013 and November 2015. For the secondary analysis, primary outcomes were between-group differences during follow-up in levels of leptin, adiponectin, ghrelin, glucagon-like peptide-1, gastric inhibitory polypeptide, peptide PYY, pancreatic polypeptide and amylin. At 56 weeks, men assigned testosterone therapy had reduced leptin levels vs. controls. Researchers noted that the between-group changes in leptin were dependent on baseline fat mass. There were no significant between-group differences for other hormones at 56 weeks, according to the researchers. The [URL="http://www.healio.com/endocrinology/hormone-therapy/news/in-the-journals/%7B7e304405-3252-40f7-b8ff-777548a84af1%7D/testosterone-therapy-decreases-leptin-levels-in-men-with-obesity"]original news report[/URL]. I have to comment that 1000 mg of testosterone a week is a huge dose, how did they ever get approval for a study like that? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone Decreases Leptin Levels in Dieting Men
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