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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Testosterone Assays
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<blockquote data-quote="madman" data-source="post: 253499" data-attributes="member: 13851"><p>My reply from a previous thread:</p><p></p><p>Regarding labs, FT assays/reference ranges.</p><p></p><p>For the time being, if you have access to such then stick to testing your FT using what would be considered the most accurate assays such as the gold standard Equilibrium Dialysis or Equilibrium Ultrafiltration (next best), especially in cases of ALTERED SHBG!</p><p></p><p>Forget getting caught up in the different reference ranges for the same assays (ED, UF) used by different labs.</p><p></p><p>Let alone trying to compare the results of ED vs UF, or ED/UF vs the cFT methods.</p><p></p><p>Test using the same lab/same assay (most accurate).</p><p></p><p>Compare your blood work using the same lab/same assay (most accurate).</p><p></p><p>Top it all off that the calculated methods even have flaws!</p><p></p><p>We need accurate and standardized free testosterone assays with harmonized reference ranges!</p><p></p><p></p><p></p><p></p><p><a href="https://www.excelmale.com/forum/threads/free-testosterone-harmonize-diagnostic-efforts-in-steroid-hormonology.27247/" target="_blank">Free Testosterone - Harmonize diagnostic efforts in steroid hormonology</a></p><p></p><p><em><strong>*Currently, the CDC is developing a <u>harmonized method for free T based on calculated free T using REVISED FORMULAE</u>. This may bring the measurement of free T to a referable standard in clinical laboratories and common reference intervals that all clinicians can use</strong></em></p><p></p><p></p><p></p><p></p><p><a href="https://www.excelmale.com/forum/threads/cdc-standardized-total-t-and-estradiol-tests-and-soon-to-be-free-testosterone.17329/" target="_blank">CDC STANDARDIZED TOTAL T AND ESTRADIOL TESTS and soon-to-be FREE TESTOSTERONE!</a></p><p></p><p><strong>Key Points:</strong></p><p><strong></strong></p><p><strong><em>* Limitations of using free testosterone by equilibrium dialysis and calculated free testosterone concentrations in practice are the <u>lack of assay standardization, an accuracy-based quality control program, and a harmonized reference range</u>. Until these <u>limitations are addressed</u>, free testosterone by equilibrium dialysis and calculated free testosterone should use <u>reference ranges established by individual laboratories or their specific assay method</u></em></strong></p><p><strong><em></em></strong></p><p><strong><em>*Assays that are <u>standardized are designed to provide accurate results, traceable to “true” value-assigned certified reference materials and gold-standard reference methods</u>. <u>Results obtained using standardized methods can be compared across assays, institutions, populations, and past and future test results, thereby improving diagnosis, treatment, and outcomes of patients</u></em></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>The Need to Harmonize Clinical Laboratory Test Results-----</strong></p><p><strong></strong></p><p><strong><em>Laboratory test results are a critical component of patient care. These values help physicians diagnose disease and are critical to developing clinical guidelines that direct treatment options and are instrumental in ongoing efforts to improve and measure the quality of patient care. <u>Most tests report a numeric value for healthcare providers to interpret and the range of numbers reported for a test for a certain condition may vary depending on the method used</u></em></strong></p><p><strong><em><u></u></em></strong></p><p><strong><em><u>Different test methods, however, may report different numeric values for the same condition</u>. <u>Although these test results may be accurate within the context of its own method, this variation can create confusion for physicians and patients</u>. Clinical laboratory test results need to be <u>harmonized</u> so that healthcare providers and the public receive the <u>same numeric result regardless of the method or instrument used or the setting where it was performed</u></em></strong></p><p></p><p></p><p></p><p></p><p></p><p>The best piece of advice is to purchase the most accurate assays through Nelson's <a href="https://www.excelmale.com/forum/threads/how-to-buy-cheap-blood-tests-online-with-discountedlabs-com.7900/" target="_blank">discountedlabs</a>.</p><p></p><p>Doubtful you will find a cheaper option when paying out of pocket.</p><p></p><p>Please support the man we all admire!</p><p></p><p></p><p></p><p></p><p><strong><u>Quest Diagnostics</u></strong></p><p><strong></strong></p><p><strong>Testosterone (T+ F), Ultrasensitive E2 & Hematocrit</strong></p><p><a href="https://www.discountedlabs.com/testosterone-total-free-ultrasensitive-estradiol-hematocrit" target="_blank">Testosterone (Total + Free), Ultrasensitive Estradiol & Hematocrit</a></p><p></p><p><strong>Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)</strong></p><p><a href="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms" target="_blank">Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)</a></p><p></p><p><strong>Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis) & Hematocrit</strong></p><p><a href="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl" target="_blank">Testosterone, Total and Free (NO Upper Limit) plus Hematocrit</a></p><p></p><p></p><p></p><p></p><p><strong>Labcorp</strong></p><p><strong></strong></p><p><strong>Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)</strong></p><p><a href="https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences" target="_blank">500726: Testosterone, Free, Mass Spectrometry/Equilibrium Dialysis (Endocrine Sciences) | Labcorp</a></p><p></p><p><strong>Testosterone, Total, LC/MS, and Free (Equilibrium Ultrafiltration)</strong></p><p><a href="https://www.labcorp.com/tests/070038/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone-lc-ms-ms" target="_blank">070038: Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone, LC/MS-MS | Labcorp</a></p></blockquote><p></p>
[QUOTE="madman, post: 253499, member: 13851"] My reply from a previous thread: Regarding labs, FT assays/reference ranges. For the time being, if you have access to such then stick to testing your FT using what would be considered the most accurate assays such as the gold standard Equilibrium Dialysis or Equilibrium Ultrafiltration (next best), especially in cases of ALTERED SHBG! Forget getting caught up in the different reference ranges for the same assays (ED, UF) used by different labs. Let alone trying to compare the results of ED vs UF, or ED/UF vs the cFT methods. Test using the same lab/same assay (most accurate). Compare your blood work using the same lab/same assay (most accurate). Top it all off that the calculated methods even have flaws! We need accurate and standardized free testosterone assays with harmonized reference ranges! [URL='https://www.excelmale.com/forum/threads/free-testosterone-harmonize-diagnostic-efforts-in-steroid-hormonology.27247/']Free Testosterone - Harmonize diagnostic efforts in steroid hormonology[/URL] [I][B]*Currently, the CDC is developing a [U]harmonized method for free T based on calculated free T using REVISED FORMULAE[/U]. This may bring the measurement of free T to a referable standard in clinical laboratories and common reference intervals that all clinicians can use[/B][/I] [URL='https://www.excelmale.com/forum/threads/cdc-standardized-total-t-and-estradiol-tests-and-soon-to-be-free-testosterone.17329/']CDC STANDARDIZED TOTAL T AND ESTRADIOL TESTS and soon-to-be FREE TESTOSTERONE![/URL] [B]Key Points: [I]* Limitations of using free testosterone by equilibrium dialysis and calculated free testosterone concentrations in practice are the [U]lack of assay standardization, an accuracy-based quality control program, and a harmonized reference range[/U]. Until these [U]limitations are addressed[/U], free testosterone by equilibrium dialysis and calculated free testosterone should use [U]reference ranges established by individual laboratories or their specific assay method[/U] *Assays that are [U]standardized are designed to provide accurate results, traceable to “true” value-assigned certified reference materials and gold-standard reference methods[/U]. [U]Results obtained using standardized methods can be compared across assays, institutions, populations, and past and future test results, thereby improving diagnosis, treatment, and outcomes of patients[/U][/I] The Need to Harmonize Clinical Laboratory Test Results----- [I]Laboratory test results are a critical component of patient care. These values help physicians diagnose disease and are critical to developing clinical guidelines that direct treatment options and are instrumental in ongoing efforts to improve and measure the quality of patient care. [U]Most tests report a numeric value for healthcare providers to interpret and the range of numbers reported for a test for a certain condition may vary depending on the method used Different test methods, however, may report different numeric values for the same condition[/U]. [U]Although these test results may be accurate within the context of its own method, this variation can create confusion for physicians and patients[/U]. Clinical laboratory test results need to be [U]harmonized[/U] so that healthcare providers and the public receive the [U]same numeric result regardless of the method or instrument used or the setting where it was performed[/U][/I][/B] The best piece of advice is to purchase the most accurate assays through Nelson's [URL='https://www.excelmale.com/forum/threads/how-to-buy-cheap-blood-tests-online-with-discountedlabs-com.7900/']discountedlabs[/URL]. Doubtful you will find a cheaper option when paying out of pocket. Please support the man we all admire! [B][U]Quest Diagnostics[/U] Testosterone (T+ F), Ultrasensitive E2 & Hematocrit[/B] [URL='https://www.discountedlabs.com/testosterone-total-free-ultrasensitive-estradiol-hematocrit']Testosterone (Total + Free), Ultrasensitive Estradiol & Hematocrit[/URL] [B]Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)[/B] [URL='https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms']Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)[/URL] [B]Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis) & Hematocrit[/B] [URL='https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl']Testosterone, Total and Free (NO Upper Limit) plus Hematocrit[/URL] [B]Labcorp Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)[/B] [URL='https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences']500726: Testosterone, Free, Mass Spectrometry/Equilibrium Dialysis (Endocrine Sciences) | Labcorp[/URL] [B]Testosterone, Total, LC/MS, and Free (Equilibrium Ultrafiltration)[/B] [URL='https://www.labcorp.com/tests/070038/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone-lc-ms-ms']070038: Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone, LC/MS-MS | Labcorp[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Testosterone Assays
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