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I have said this several times: Doses under 500 IU are needed for 70% of men on HCG to respond while on TRT ( for HCG monotherapy at least 1500 IU 3 times per week). They have to reach that peak. Study data available on frequency shows that 3 times per week of HCG plus TRT was able to normalize sperm count on 70% of men. The 30% that did not respond well were older and on TRT the longest prior to adding HCG. Data from Lipshultz group at Baylor College of Medicine here in Houston.


I would give myself a booster shot of 1000 IU of HCG and then continue with 500 IU twice per week two days after that booster shot. If in 3 weeks there is no normalization of my testicular size, I would stop HCG and carry on with TRT only.


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