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I take enanthate; 160mg would be way to high for me.  I took 84mg/wk before cutting down to 77mg/wk.  At 84mg/week my TT was 29.4 (normal 8.4 - 28.8) and my free T was 723 (170-475); I also had lipids that were negatively affected, as well as higher hemoglobin and hematocrit.  As you can see, cutting down to 77mg/wk should still leave my T in a good place while benefiting the rest of the profile.  Granted, I've always been a good responder to meds, but other people are too.  What would happen if I started at 200 mg/wk or even 160?