A reasonable starting protocol is 40 mg twice a week, or 25 mg three times a week. This is one area where I criticize Defy. It's ridiculous to start somebody on a protocol that provides more than double high-end natural production of testosterone. That is, the normal range of testosterone production is 3-9 mg per day, with 6-7 mg being typical for healthy young guys. In contrast, you're starting with 16 mg per day. While some guys get away with this, others end up pretty miserable with various side effects. You can read some anecdotes here:
[URL unfurl="true"]https://www.excelmale.com/threads/answering-some-questions-new-to-forum-much-appreciated.26955/#post-245316[/URL]
When it comes to hormones, a low-and-slow approach is usually going to be best. That is, start with a low-end dose, and only increase slowly, if needed, to attain resolution of symptoms. The only possible exception is if you value body composition and athleticism over overall health. Then you might be willing to risk the consequences of taking supraphysiological amounts of testosterone.