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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Tesamorelin vs. Ipamorelin?
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<blockquote data-quote="Cataceous" data-source="post: 172771" data-attributes="member: 38109"><p>Says the guy whose reference contradicts his viewpoint.</p><p></p><p>Even the cheerleading article in the Lifespan Journal acknowledges:</p><p></p><p style="margin-left: 20px"><em>A not negligible number of studies have shown a positive association between higher serum IGF-1 levels and increased risk of breast cancer...</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>Some evidence points to the possibility that colon cancer might be favored by increased IGF-1 levels...</em></p> <p style="margin-left: 20px"></p><p>This piece uses the problems seen with low levels to argue in favor of high levels. But they conveniently overlook the unfavorable mortality studies and the lack of diabetes and cancer in those with <a href="https://www.nytimes.com/2011/02/17/science/17longevity.html?_r=1&hpw" target="_blank">Laron syndrome</a>.</p><p></p><p style="margin-left: 20px"><em>Dr. Longo said he believed that having very low levels of IGF-1 was the critical feature of the Laron patients’ freedom from age-related diseases. In collaboration with Dr. Guevara-Aguirre, he exposed human cells growing in a laboratory dish to serum from the Laron patients. The cells were then damaged with a chemical that disrupts their DNA. The Laron serum had two significant effects, <a href="http://stm.sciencemag.org/content/3/70/70ra13.abstract" target="_blank">the two physicians reported on Wednesday in Science Translational Medicine</a>.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>First, the serum protected the cells from genetic damage. Second, it spurred the cells that were damaged to destroy themselves, a mechanism the body uses to prevent damaged cells from becoming cancerous. Both these effects were reversed when small amounts of IGF-1 were added to the serum.</em></p></blockquote><p></p>
[QUOTE="Cataceous, post: 172771, member: 38109"] Says the guy whose reference contradicts his viewpoint. Even the cheerleading article in the Lifespan Journal acknowledges: [INDENT][I]A not negligible number of studies have shown a positive association between higher serum IGF-1 levels and increased risk of breast cancer...[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]Some evidence points to the possibility that colon cancer might be favored by increased IGF-1 levels...[/I][/INDENT] [INDENT][/INDENT] This piece uses the problems seen with low levels to argue in favor of high levels. But they conveniently overlook the unfavorable mortality studies and the lack of diabetes and cancer in those with [URL='https://www.nytimes.com/2011/02/17/science/17longevity.html?_r=1&hpw']Laron syndrome[/URL]. [INDENT][I]Dr. Longo said he believed that having very low levels of IGF-1 was the critical feature of the Laron patients’ freedom from age-related diseases. In collaboration with Dr. Guevara-Aguirre, he exposed human cells growing in a laboratory dish to serum from the Laron patients. The cells were then damaged with a chemical that disrupts their DNA. The Laron serum had two significant effects, [URL='http://stm.sciencemag.org/content/3/70/70ra13.abstract']the two physicians reported on Wednesday in Science Translational Medicine[/URL].[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]First, the serum protected the cells from genetic damage. Second, it spurred the cells that were damaged to destroy themselves, a mechanism the body uses to prevent damaged cells from becoming cancerous. Both these effects were reversed when small amounts of IGF-1 were added to the serum.[/I][/INDENT] [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Tesamorelin vs. Ipamorelin?
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