Thats one mechanism why telmisartan has neuroprotective effects, because it increases prolactin and lowers dopamine. This is totally turn off for me. Because i personally would rather increase dopamine and lower prolactin.
[URL unfurl="true"]https://iej.zaslavsky.com.ua/index.php/journal/article/view/1142[/URL]
While treating with telmisartan, the level of prolactin in males of the experimental group increased significantly, whereas in the comparison group, it did not change dramatically. Therefore, a considerable increase of prolactin levels in males and females was observed in telmisartan treatment.
Conclusions. The use of telmisartan as a part of combined therapy facilitates the reduction of the cortisol level (p > 0.05) and leads to a significant rise in male and female prolactin levels (within the range of reference values).
[URL unfurl="true"]https://www.researchgate.net/figure/Repair-mechanisms-of-MMP-9-inhibitors-prolactin-and-various-renin-angiotensin-system_fig2_355172230[/URL]
Telmisartan reduces angiotensin II and thus lowers dopamine levels.
Prolactin down-regulates dopamine and also protects the blood-brain barrier from damage.
