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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Target T levels & Defy
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<blockquote data-quote="xqfq" data-source="post: 169350" data-attributes="member: 38167"><p>It turns out I have had equilibrium dialysis performed. These are results from Quest’s lab order code 36170, which is stated to be MS for total testosterone and equilibrium dialysis for free testosterone, as per <a href="https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&cc=MASTER" target="_blank"><span style="font-size: 16px">https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&cc=MASTER</span></a></p><p></p><p>Testosterone 1074</p><p>Free testosterone 155.5 pg/mL = 15.55 ng/dL.</p><p>(Range: 35.0-155.0 pg/mL)</p><p></p><p>My SHBG, as measured a few days prior in a separate lab, was 48. Using the TruT calculator, my free T is expected to be 34.59 ng/dL, which is over twice as much as dialysis states. To have the calculator be accurate, my SHBG would have to have been 200+, which I consider nearly impossible.</p><p></p><p>Another of the same lab during another checkup:</p><p></p><p>T 902</p><p>Free T 144.3 pg/mL (Range: 35.0-155.0 pg/mL)</p><p>= 14.4 ng/dL</p><p></p><p>TruT puts me at 30.83 ng/dL according to an SHBG of ~36 drawn a few days later. Again TruT is off by over 2x.</p><p></p><p>In my case, TruT is not remotely accurate. Perhaps I’m missing something and the Quest lab test is reporting figures in some kind of units that only apply to their test and can’t be generalized to the same values as TruT. E.g. these reference ranges and units aren’t aligned somehow?</p><p></p><p>According to this source (<a href="https://www.researchgate.net/publication/257347511_Free_testosterone_by_direct_and_calculated_measurement_versus_equilibrium_dialysis_in_a_clinical_population" target="_blank"><span style="font-size: 16px">https://www.researchgate.net/publication/257347511_Free_testosterone_by_direct_and_calculated_measurement_versus_equilibrium_dialysis_in_a_clinical_population</span></a>), “<span style="color: rgb(17, 17, 17)"> These results support the clinical use of both RIA and cFT as measures of FT. Due to numerical differences, each test requires its own set of reference values.“</span></p><p></p><p>If anyone has an idea, please chime in!</p></blockquote><p></p>
[QUOTE="xqfq, post: 169350, member: 38167"] It turns out I have had equilibrium dialysis performed. These are results from Quest’s lab order code 36170, which is stated to be MS for total testosterone and equilibrium dialysis for free testosterone, as per [URL='https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&cc=MASTER'][SIZE=16px]https://testdirectory.questdiagnostics.com/test/test-detail/36170/testosterone-free-dialysis-and-total-ms?p=r&cc=MASTER[/SIZE][/URL] Testosterone 1074 Free testosterone 155.5 pg/mL = 15.55 ng/dL. (Range: 35.0-155.0 pg/mL) My SHBG, as measured a few days prior in a separate lab, was 48. Using the TruT calculator, my free T is expected to be 34.59 ng/dL, which is over twice as much as dialysis states. To have the calculator be accurate, my SHBG would have to have been 200+, which I consider nearly impossible. Another of the same lab during another checkup: T 902 Free T 144.3 pg/mL (Range: 35.0-155.0 pg/mL) = 14.4 ng/dL TruT puts me at 30.83 ng/dL according to an SHBG of ~36 drawn a few days later. Again TruT is off by over 2x. In my case, TruT is not remotely accurate. Perhaps I’m missing something and the Quest lab test is reporting figures in some kind of units that only apply to their test and can’t be generalized to the same values as TruT. E.g. these reference ranges and units aren’t aligned somehow? According to this source ([URL='https://www.researchgate.net/publication/257347511_Free_testosterone_by_direct_and_calculated_measurement_versus_equilibrium_dialysis_in_a_clinical_population'][FONT=Open Sans][SIZE=16px]https://www.researchgate.net/publication/257347511_Free_testosterone_by_direct_and_calculated_measurement_versus_equilibrium_dialysis_in_a_clinical_population[/SIZE][/FONT][/URL]), “[FONT=Roboto][COLOR=rgb(17, 17, 17)] These results support the clinical use of both RIA and cFT as measures of FT. Due to numerical differences, each test requires its own set of reference values.“[/COLOR][/FONT] If anyone has an idea, please chime in! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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