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Taking blood pressure meds at night
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<blockquote data-quote="Biobro" data-source="post: 227399" data-attributes="member: 43789"><p>I should note that, nebivolol would be exeption, it doesnt fuck up your sleep parameters, inhibit melatonin etc, as long as you dont dose it too high that it loses its selectivity or crosses blood brain barrier too much. I take it 2.5mg daily.</p><p></p><p>1:</p><p>”A trial investigating three β-blockers showed that bisoprolol, but not nebivolol or carvedilol, decreased nocturnal release of melatonin, a phenomenon that may cause sleep disturbances.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310359/#b85-vhrm-8-151" target="_blank">85</a> This study also showed that carvedilol slightly decreased quality of life, whereas nebivolol and bisoprolol had no influence, suggesting that different β-blockers exert different clinically relevant effects.”</p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310359/[/URL]</p><p></p><p>2:</p><p>Conclusion</p><p>”Nebivolol was associated with improved sleep, whereas metoprolol was associated with a worsening of sleep characteristics.”</p><p>[URL unfurl="true"]https://link.springer.com/article/10.1007/s12325-008-0087-x[/URL]</p><p></p><p>3:</p><p>”As a further feature, it was shown that Nebivolol <strong>does not decrease nocturnal melatonin release”</strong></p><p>[URL unfurl="true"]https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-6/Individual-beta-blockers-for-individual-patients-Title-Individual-beta-blocke[/URL]</p></blockquote><p></p>
[QUOTE="Biobro, post: 227399, member: 43789"] I should note that, nebivolol would be exeption, it doesnt fuck up your sleep parameters, inhibit melatonin etc, as long as you dont dose it too high that it loses its selectivity or crosses blood brain barrier too much. I take it 2.5mg daily. 1: ”A trial investigating three β-blockers showed that bisoprolol, but not nebivolol or carvedilol, decreased nocturnal release of melatonin, a phenomenon that may cause sleep disturbances.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310359/#b85-vhrm-8-151']85[/URL] This study also showed that carvedilol slightly decreased quality of life, whereas nebivolol and bisoprolol had no influence, suggesting that different β-blockers exert different clinically relevant effects.” [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310359/[/URL] 2: Conclusion ”Nebivolol was associated with improved sleep, whereas metoprolol was associated with a worsening of sleep characteristics.” [URL unfurl="true"]https://link.springer.com/article/10.1007/s12325-008-0087-x[/URL] 3: ”As a further feature, it was shown that Nebivolol [B]does not decrease nocturnal melatonin release”[/B] [URL unfurl="true"]https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-6/Individual-beta-blockers-for-individual-patients-Title-Individual-beta-blocke[/URL] [/QUOTE]
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Taking blood pressure meds at night
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