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Doctor and Clinic Reviews
T3 & Total Testosterone
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<blockquote data-quote="Vettester Chris" data-source="post: 67458" data-attributes="member: 696"><p>OK, at 20mcg of Cytomel, your FT3 serum is yielding 8.3pg/ml, and to boot your RT3 ratio is still 19.3. The concerning part is that you're not even taking any T4 or T4/T3 combo NDT, but RT3 is up! This is a key marker that lets you know something is amiss!!</p><p></p><p>On the scale of thyroid meds, 20mcg of T3 Cytomel is less than 1 Grain of NDT, actually approx. 80% of just 1 grain. That shouldn't even be enough to get you to 50% or 60% of the reference range on FT3, let alone anywhere near that level. </p><p></p><p>T3 either ... </p><p>1) Gets transported to the cells and does its magic. </p><p>2) or it is unable to get transported to the cells and goes nowhere.</p><p></p><p>When T3 goes nowhere, serum levels rise, that's referred to as "Pooling". The body's main mechanism to balance this event is to shift a fair concentration of T4 conversion to RT3. Since you're bypassing the natural process of this event by supplementing Cytomel T3, it can only proceed on a forward path, which again either makes it to the cells or it doesn't. Even more baffling, how does your T4 go over the top when taking T3 medication??</p><p></p><p>IMO, you need to look primarily at iron serum, TIBC, ferritin, full 24 hour cortisol. Those are KEY critical areas that have to be decent in order for T3 to work. Supporting labs beyond that will be your electrolytes, D3, B12, and I'm real curious what your Antibody tests look like; both TgAb and TPO? FT4 is even over the top, something is WAY off!! (this at least explains where the RT3 conversion is coming from)!</p></blockquote><p></p>
[QUOTE="Vettester Chris, post: 67458, member: 696"] OK, at 20mcg of Cytomel, your FT3 serum is yielding 8.3pg/ml, and to boot your RT3 ratio is still 19.3. The concerning part is that you're not even taking any T4 or T4/T3 combo NDT, but RT3 is up! This is a key marker that lets you know something is amiss!! On the scale of thyroid meds, 20mcg of T3 Cytomel is less than 1 Grain of NDT, actually approx. 80% of just 1 grain. That shouldn't even be enough to get you to 50% or 60% of the reference range on FT3, let alone anywhere near that level. T3 either ... 1) Gets transported to the cells and does its magic. 2) or it is unable to get transported to the cells and goes nowhere. When T3 goes nowhere, serum levels rise, that's referred to as "Pooling". The body's main mechanism to balance this event is to shift a fair concentration of T4 conversion to RT3. Since you're bypassing the natural process of this event by supplementing Cytomel T3, it can only proceed on a forward path, which again either makes it to the cells or it doesn't. Even more baffling, how does your T4 go over the top when taking T3 medication?? IMO, you need to look primarily at iron serum, TIBC, ferritin, full 24 hour cortisol. Those are KEY critical areas that have to be decent in order for T3 to work. Supporting labs beyond that will be your electrolytes, D3, B12, and I'm real curious what your Antibody tests look like; both TgAb and TPO? FT4 is even over the top, something is WAY off!! (this at least explains where the RT3 conversion is coming from)! [/QUOTE]
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T3 & Total Testosterone
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