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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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<blockquote data-quote="johndoesmith" data-source="post: 73248" data-attributes="member: 13404"><p>Generally when it's calculated, units aren't changed. Most of the time testosterone is in ng/dl and E2 is in pg/ml. </p><p></p><p>Sometimes E2 will be in pmol/l which generally 40 pmol/l = 10 pg/ml. All pmol/l tests are standard assays, because they're almost always from non united states labs. I believe I've seen one sensitive assay from Australia but that's the only other country I know of that has it. </p><p></p><p>T/E2 ratio is a guide, not a perfect tool that applies in all situations. My T/E2 ratio on TRT is about 30, where generally 14-20 is stated to be the target range. My pre TRT ratio was 50 or so, in this case a higher number = less aromatization. TRT will cause more aromatization because of the AUC(area under the curve) increasing. There aren't large diurnal variations like with a natty guy's testosterone that drops off during the day. </p><p></p><p>That's something to keep in mind. When a guy's initial labs show 300 total test and E2 at 30, he's going to have E2 issues on TRT, even without accounting for the higher aromatization on TRT. Basic math indicates that at 900 he'd have an E2 of 90, this isn't always the case but he's certainly going to have a rather high E2 level on TRT, and thus starting TRT with a low dose of AI would be a good idea.</p></blockquote><p></p>
[QUOTE="johndoesmith, post: 73248, member: 13404"] Generally when it's calculated, units aren't changed. Most of the time testosterone is in ng/dl and E2 is in pg/ml. Sometimes E2 will be in pmol/l which generally 40 pmol/l = 10 pg/ml. All pmol/l tests are standard assays, because they're almost always from non united states labs. I believe I've seen one sensitive assay from Australia but that's the only other country I know of that has it. T/E2 ratio is a guide, not a perfect tool that applies in all situations. My T/E2 ratio on TRT is about 30, where generally 14-20 is stated to be the target range. My pre TRT ratio was 50 or so, in this case a higher number = less aromatization. TRT will cause more aromatization because of the AUC(area under the curve) increasing. There aren't large diurnal variations like with a natty guy's testosterone that drops off during the day. That's something to keep in mind. When a guy's initial labs show 300 total test and E2 at 30, he's going to have E2 issues on TRT, even without accounting for the higher aromatization on TRT. Basic math indicates that at 900 he'd have an E2 of 90, this isn't always the case but he's certainly going to have a rather high E2 level on TRT, and thus starting TRT with a low dose of AI would be a good idea. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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