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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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<blockquote data-quote="Nelson Vergel" data-source="post: 136638" data-attributes="member: 3"><p>Not sure if I have seen data that shows that as DHT increases along with T there is actually an increase of E2 just solely because of the effect of DHT on estrogen receptors. This is hard to prove since as T increases, so does E2 along with DHT.</p><p></p><p>T, DHT, and estradiol all bind to SHBG. SHBG decreases with increased T dose. So, free DHT, free T, and free E2 may raise. But free E2 may actually be protective in older men at least when it comes to cerebrovascular disease, as shown above.</p><p></p><p>I would love for someone here to review that paper. I am short of time but would welcome actual analysis instead of opinions.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 136638, member: 3"] Not sure if I have seen data that shows that as DHT increases along with T there is actually an increase of E2 just solely because of the effect of DHT on estrogen receptors. This is hard to prove since as T increases, so does E2 along with DHT. T, DHT, and estradiol all bind to SHBG. SHBG decreases with increased T dose. So, free DHT, free T, and free E2 may raise. But free E2 may actually be protective in older men at least when it comes to cerebrovascular disease, as shown above. I would love for someone here to review that paper. I am short of time but would welcome actual analysis instead of opinions. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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