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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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<blockquote data-quote="Nelson Vergel" data-source="post: 136583" data-attributes="member: 3"><p style="margin-left: 20px">Very little data on T/E2 ratios (that actually use LC/MS for both parameters).</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">My hypothesis is that, like all hormones, there is an inverted U-shaped curve (for benefits vs T/E2 ratio). Some studies hint at T/E2 above 14, but we have no data on the upper range since very high T/E2 may be indicative of low estradiol.</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">Post #12: <a href="https://www.excelmale.com/forum/threads/is-testosterone-to-estradiol-ratio-important-in-men.4921/" target="_blank">Is Testosterone to Estradiol Ratio Important in Men?</a></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">Since 0.3 percent of TT is normally aromatized into E2 in healthy men, then it makes sense that</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">1/0.03= 33 (both in ng/dL)</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">Estradiol tends to plateau as T dose increases (probably also due to increased DHT that acts as an estradiol blocker). Aromatization was shown to be higher for older men here:</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><a href="https://www.excelmale.com/effect-of-testosterone-injections-on-estradiol-and-dht-in-young-and-older-men/" target="_blank">Effect of Testosterone Injections on Estradiol and DHT in Young and Older Men - ExcelMale</a></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px">I think 0.25 mg per week of anastrozole makes sense for men whose conversion is above 0.3 percent (I think we should monitor estradiol like we do free T. Free T percent should be 2% of TT or above). DHT should be 10% of TT or above.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 136583, member: 3"] [INDENT]Very little data on T/E2 ratios (that actually use LC/MS for both parameters).[/INDENT] [INDENT][/INDENT] [INDENT]My hypothesis is that, like all hormones, there is an inverted U-shaped curve (for benefits vs T/E2 ratio). Some studies hint at T/E2 above 14, but we have no data on the upper range since very high T/E2 may be indicative of low estradiol.[/INDENT] [INDENT][/INDENT] [INDENT]Post #12: [URL='https://www.excelmale.com/forum/threads/is-testosterone-to-estradiol-ratio-important-in-men.4921/']Is Testosterone to Estradiol Ratio Important in Men?[/URL][/INDENT] [INDENT][/INDENT] [INDENT]Since 0.3 percent of TT is normally aromatized into E2 in healthy men, then it makes sense that[/INDENT] [INDENT][/INDENT] [INDENT]1/0.03= 33 (both in ng/dL)[/INDENT] [INDENT][/INDENT] [INDENT]Estradiol tends to plateau as T dose increases (probably also due to increased DHT that acts as an estradiol blocker). Aromatization was shown to be higher for older men here:[/INDENT] [INDENT][/INDENT] [INDENT][URL='https://www.excelmale.com/effect-of-testosterone-injections-on-estradiol-and-dht-in-young-and-older-men/']Effect of Testosterone Injections on Estradiol and DHT in Young and Older Men - ExcelMale[/URL][/INDENT] [INDENT][/INDENT] [INDENT]I think 0.25 mg per week of anastrozole makes sense for men whose conversion is above 0.3 percent (I think we should monitor estradiol like we do free T. Free T percent should be 2% of TT or above). DHT should be 10% of TT or above.[/INDENT] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
T:E Ratio: How Do I Calculate It?
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