Case Study: Absorption of Testosterone Cream via Scrotal Delivery
In this case study it was shown that after application (200 mg dose) that therapeutic levels with concentrations of 1204.7 ng/dL were reached within 2 hrs and consistent concentrations of 1320.6 remained beyond 6 hrs.
Case Study: Absorption of Testosterone Cream via Scrotal Delivery.
Abstract
Transdermal testosterone has been used for years to treat patients with low testosterone symptoms. Clinically, we have monitored patients to evaluate results of testosterone absorption via blood serum concentrations. The data on multiple time points to determine trough and peak concentrations is lacking in the literature. In this case study, we demonstrate the absorption of testosterone cream via scrotal delivery. The data suggests that after application therapeutic levels are reached with concentrations of (1204.7 ng/dL) within two hours. Additionally, consistent concentrations (1320.6 ng/dL) remain beyond six hours. To our knowledge, this is the first study to collect and measure multiple time points for testosterone via transdermal delivery. The research indicates that testosterone via transdermal delivery is an excellent method to achieve therapeutic concentrations of testosterone. Most importantly, the patient's symptoms resolved without side effects.
PMID: 30384346
