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Message: <blockquote data-quote="madman" data-source="post: 281556" data-attributes="member: 13851">[URL unfurl="true"]https://www.excelmale.com/threads/discouraged-with-trt.30409/page-3[/URL]post #53*I think Cataceous made a pretty strong argument supporting the concept that the norm of starting us all at 100mg per week is excessive . . . and then when it doesn't work well most are inclined to take more instead of less. I'm still very new to all of this, but I'm drawn to the "less is more" idea and have now reduced my originally prescribed dose by 15%. Probably worth a try for you, maybe 75mg per week instead of 100?Hate to be the bearer of bad news here but the most common starting dose is 100 mg T/week.Most in the know including many of the top uros preach this!Look up Dr. Morgentaler who would be considered the godfather of testosterone.Most men on TTh are injecting 100-200 mg T/week whether once weekly or split into more frequent injections as in twice-weekly, 3X/week, EOD or daily.Even then the majority of men can easily hit a healthy/high trough FT injecting 100-150 mg T/week especially when split into more frequent injections.Yes there will always be those outliers who need the higher-end dose but this is far from common as in rare!200 mg T/week is overkill for the majority!Yes there are some men who can achieve stellar T levels injecting <100 mg T/week especially when split into more frequent injections but it is far from common.Unfortunately most men especially the ones caught up on those so called men's health forums loaded with all those blast n cruizzzers littered on the internet let alone the nonsense being pushed by those dime a dozen run of the mill T-clinics or so called internet gurus have these men brainwashed into thinking they need to be hitting this so called magical trough FT 30-60 ng/dL in order to reap the beneficial effects of testosterone.That more T is better mentality bullS**T!Top it off when using exogenous testosterone for most we are forcing levels well beyond what our body could or would produce and this is at a steady state (24/7).The shit kicker here is most are running trough levels at the top-end or well beyond!Most men have blown past their genetic set-point let alone are running around with inflated FT levels well beyond where a healthy young male would sit (peak)  and this is inflated trough levels we are talking about here which means that their peak FT levels will be even higher.Again the average secretion rate of T in the majority of healthy young males is 5-7 mg/day.10 mg would be those outliers and even then there is not going to be a big difference in how one would feel/function.Also need to keep in mind that those healthy natty young men running around with those very high T levels have high SHBG and it is not like they are running around with absurdly high FT levels.Top it off that these TT/FT levels healthy natty young men in their prime are hitting are at peak which is short-lived, their trough/nadir (lowest point)) of the day would be 20-25% lower.Natural endogenous testosterone secretion is pulsatile and diurnal.During the natural 24-hour circadian rhythm of a healthy young male T levels will start rising gradually overnight reaching a peak (highest point) in the early AM followed by lower levels in the late afternoon and reaching trough (lowest point) in the evening.Fluctuations from peak--->trough would be around 20-25%One daily peak/trough.What percentile of healthy young men would even be hitting a peak not trough FT 17.1 ng/dL!LMFAO![URL unfurl="true"]https://www.excelmale.com/threads/age-stratified-reference-ranges-for-directly-measured-ed-lc-ms-ms-serum-free-testosterone-in-healthy-men.30376/[/URL]<table style='width: 100%'><tr><td> Age category (years) </td><td> Median mFT (ng/dl) </td><td> 95% mFT reference range (ng/dl) </td></tr><tr><td> 25-29 (n=148) </td><td> 10.3 </td><td> 5.6 - 17.1 </td></tr></table>[URL unfurl="true"]https://www.excelmale.com/threads/a-pill-that-could-outsell-viagra-new-testosterone-rx-drug.26222/#post-235690[/URL][URL unfurl="true"]https://www.excelmale.com/threads/testosterone-therapy-tth-how-to-treat-abraham-morgentaler.28911/#post-270279[/URL]Dose T/weekThe starting dose is about 100 mg/week.If they're going to be giving it to themselves or coming into the office every week we start with 100 mg but you can move up.Rarely do we go lower but some people will.100 mg is 0.5 CC each CC is 200 mg per CC or per mL.So we start at 0.5 and if that's not good enough we go to 0.6 (120 mg) and 0.7 (140 mg) and occasionally but not very often we go above that</blockquote>

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