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General Health & Fitness
Health & Wellness
Supercharge Your Health: The Nitric Oxide Revolution!
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<blockquote data-quote="madman" data-source="post: 259958" data-attributes="member: 13851"><p>Eye-opener!</p><p></p><p><strong>30:42-35:46</strong></p><p></p><p></p><p>The main driver as to why some men are non-responders!</p><p></p><p><strong>31:17-32:36</strong></p><p><strong></strong></p><p><strong><em>*Well it shows us that really if you can maintain blood flow then you know a lot of times you don't get this chronic dysfunction that leads to chronic disease so Viagra or what we call <u>phosphodiesterase inhibitors are dependent upon nitric oxide production so these aren't nitric oxide generating drugs they potentiate nitric oxide</u> so if you are able to produce a little bit of nitric oxide and then it activates an enzyme called Guanylate cyclase leads to increase in cyclic GMP and these PDE5 inhibitors prevent the breakdown of a second messenger so you can actually you know <u>sensitize the system</u> that is why they work for improving erectile dysfunction</em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em>*The problem is you know these drugs were approved I believe in 1998 so over 25 years on the market and you know they only work in about 40-50% of the men in which they are prescribed so these <u>non-responders mechanistically are none responders because their bodies are not making any nitric oxide to activate the system for these drugs to work on</u> so we can now if you restore nitric oxide you can turn non-responders into responders than the end result is vasodilation and <u>vasodilation leads to increase in oxygen and nutrient delivery to every organ, tissue, and cell in the body</u></em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 259958, member: 13851"] Eye-opener! [B]30:42-35:46[/B] The main driver as to why some men are non-responders! [B]31:17-32:36 [I]*Well it shows us that really if you can maintain blood flow then you know a lot of times you don't get this chronic dysfunction that leads to chronic disease so Viagra or what we call [U]phosphodiesterase inhibitors are dependent upon nitric oxide production so these aren't nitric oxide generating drugs they potentiate nitric oxide[/U] so if you are able to produce a little bit of nitric oxide and then it activates an enzyme called Guanylate cyclase leads to increase in cyclic GMP and these PDE5 inhibitors prevent the breakdown of a second messenger so you can actually you know [U]sensitize the system[/U] that is why they work for improving erectile dysfunction *The problem is you know these drugs were approved I believe in 1998 so over 25 years on the market and you know they only work in about 40-50% of the men in which they are prescribed so these [U]non-responders mechanistically are none responders because their bodies are not making any nitric oxide to activate the system for these drugs to work on[/U] so we can now if you restore nitric oxide you can turn non-responders into responders than the end result is vasodilation and [U]vasodilation leads to increase in oxygen and nutrient delivery to every organ, tissue, and cell in the body[/U][/I][/B] [/QUOTE]
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Supercharge Your Health: The Nitric Oxide Revolution!
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