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Can you post the full lab results? Something is missing here.

You had 2 blood tests drawn, so you went back to the lab within 3 days, correct?

I actually think this is a combination of low SHBG like coastwatcher said, along with a lab error. 2200 ng/dl is significantly higher than what would make sense, and your E2 barely drops even though total testosterone decreases by a factor of nearly 4.

There is no sense in testing 36 hours after or 5 days after. Test trough, day of injection, but before injection. Any other time offers little to no actionable information.