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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Suicide Inhibitor like Aromasin/Exemestane
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<blockquote data-quote="Appassionato" data-source="post: 141359" data-attributes="member: 37892"><p>That's one of the biggest study on exemestane, that took in account several hormones reaction with the administration of it:</p><p></p><p><a href="https://academic.oup.com/jcem/article/88/12/5951/2661508" target="_blank">Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males</a></p><p></p><p>The interesting thing is that the drug has a different behaviour at a 25mg daily administration compared with the 50mg. In any case, you don't want to use any of these doses, unless you want to make your E2 undetectable:</p><p></p><p><span style="font-size: 15px"><span style="color: rgb(42, 42, 42)">Serum cortisol concentrations increased significantly (38 ± 39%; </span></span><span style="color: rgb(42, 42, 42)"><em><span style="font-size: 15px">P</span></em></span><span style="font-size: 15px"><span style="color: rgb(42, 42, 42)"> = 0.008) with the 25-mg dose, but not the 50-mg dose, yet the increase was well within the normal range of cortisol concentrations.</span></span></p><p></p><p>Other studies showed no difference in cortisol after the administration, so there's definitely something tricky going on with the different doses.</p></blockquote><p></p>
[QUOTE="Appassionato, post: 141359, member: 37892"] That's one of the biggest study on exemestane, that took in account several hormones reaction with the administration of it: [URL="https://academic.oup.com/jcem/article/88/12/5951/2661508"]Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males[/URL] The interesting thing is that the drug has a different behaviour at a 25mg daily administration compared with the 50mg. In any case, you don't want to use any of these doses, unless you want to make your E2 undetectable: [SIZE=15px][FONT=Merriweather][COLOR=rgb(42, 42, 42)]Serum cortisol concentrations increased significantly (38 ± 39%; [/COLOR][/FONT][/SIZE][COLOR=rgb(42, 42, 42)][I][SIZE=15px][FONT=Merriweather]P[/FONT][/SIZE][/I][/COLOR][SIZE=15px][FONT=Merriweather][COLOR=rgb(42, 42, 42)] = 0.008) with the 25-mg dose, but not the 50-mg dose, yet the increase was well within the normal range of cortisol concentrations.[/COLOR][/FONT][/SIZE] Other studies showed no difference in cortisol after the administration, so there's definitely something tricky going on with the different doses. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Suicide Inhibitor like Aromasin/Exemestane
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