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Anastozole is going to be counterproductive if you already have osteopenia. Also, estradiol isn't necessarily the primary culprit in fluid retention. Before considering a host of other drugs to combat this side effect, why not see if you can avoid it from the start with physiological dosing? The average healthy young man makes 6-7 mg of testosterone daily. There's no reason to start TRT with a higher dose than this. The equivalent in testosterone cypionate is 60-70 mg per week. This should be split into at least two doses per week, and ideally would be split into every-other-day dosing, so that excessive peaks in serum testosterone are avoided.

If you have problems with modest doses of cypionate then there's still the option to experiment with propionate blends, which have anecdotal support for decreasing fluid retention.