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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Success stories for managing TRT induced increase in hematocrit?
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<blockquote data-quote="Cataceous" data-source="post: 192872" data-attributes="member: 38109"><p>I'm getting the sense that testosterone troches might behave a little like Natesto, the nasal testosterone gel. This would make it short acting and quite different from conventional TRT. If this is the case then the transition could be challenging. The idea behind Natesto is to supplement natural testosterone production rather than replace it. In your case it will take some time to restart natural production, and use of testosterone will slow down that restart. If this is what's expected then I'm not sure what kind of subjective experience you'll get from spiking testosterone a few times a day while having very low levels before doses and overnight.</p><p></p><p>Reported absorption rates for troches are quite variable, up to 50%, but as low as 10%.</p><p></p><p style="margin-left: 20px"><em>Troches also exhibit poor pharmacokinetic parameters. This means that there are great fluctuations in hormone serum levels after taking a troche dose. Soon after taking a troche serum hormone levels rise rapidly, sometimes to very high levels, and then rapidly fall to low levels within 4 to 5 hours. They therefore require at least twice daily administration or for optimal results three to four times a day to maintain adequate levels longer however compliance becomes a major problem with this type of dosing schedule.</em></p><p>[<a href="https://custommedicine.com.au/health-articles/the-truth-about-troches/" target="_blank">R</a>]</p></blockquote><p></p>
[QUOTE="Cataceous, post: 192872, member: 38109"] I'm getting the sense that testosterone troches might behave a little like Natesto, the nasal testosterone gel. This would make it short acting and quite different from conventional TRT. If this is the case then the transition could be challenging. The idea behind Natesto is to supplement natural testosterone production rather than replace it. In your case it will take some time to restart natural production, and use of testosterone will slow down that restart. If this is what's expected then I'm not sure what kind of subjective experience you'll get from spiking testosterone a few times a day while having very low levels before doses and overnight. Reported absorption rates for troches are quite variable, up to 50%, but as low as 10%. [INDENT][I]Troches also exhibit poor pharmacokinetic parameters. This means that there are great fluctuations in hormone serum levels after taking a troche dose. Soon after taking a troche serum hormone levels rise rapidly, sometimes to very high levels, and then rapidly fall to low levels within 4 to 5 hours. They therefore require at least twice daily administration or for optimal results three to four times a day to maintain adequate levels longer however compliance becomes a major problem with this type of dosing schedule.[/I][/INDENT] [[URL='https://custommedicine.com.au/health-articles/the-truth-about-troches/']R[/URL]] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Success stories for managing TRT induced increase in hematocrit?
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